Socially induced and rapid increases in aggression are inversely related to brain aromatase activity in a sex-changing fish, Lythrypnus dalli
Socially induced and rapid increases in aggression are inversely related to brain aromatase activity in a sex-changing fish, Lythrypnus dalli
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DOI：
10.1098/rspb.2005.3210
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发表时间：
2005-11-22
影响因子：
4.7
通讯作者：
Grober, MS
中科院分区：
文献类型：
--
作者：
Black, MP;Balthazart, J;Grober, MS
社会互动可以在行为和神经内分泌活动中产生快速和戏剧性的变化。我们调查了一个不断变化的社会环境对攻击性行为和脑芳香化酶活性（bAA）的性别变化的鱼，Lythrypnus dalli的影响。芳香酶负责将雄激素转化为雌激素。从社会稳定的群体中移除雄性会导致占主导地位的雌性的攻击性迅速而戏剧性地增加（>= 200%），这些雌性通常在7-10天后变成雄性。这些占主导地位的女性和最近性别改变的个人有较低的bAA，但类似的性腺芳香化酶活性（gAA）相比，控制女性，而建立男性有较低的bAA比所有组和较低的gAA比所有组，除了占主导地位的女性。在几个小时内的男性去除，占主导地位的女性的攻击行为呈负相关，bAA，但不gAA。这些结果是新颖的，因为它们是第一个：（i）证明社会诱导的bAA水平降低相应的增加侵略，（ii）确定这一过程作为一个可能的神经化学机制，调节诱导行为，随后性腺，性别变化和（iii）显示差异调节bAA与gAA的社会操纵。结合其他研究，这表明芳香化酶活性可能调节脊椎动物社会行为的快速变化。
Social interactions can generate rapid and dramatic changes in behaviour and neuroendocrine activity. We investigated the effects of a changing social environment on aggressive behaviour and brain aromatase activity (bAA) in a sex-changing fish, Lythrypnus dalli. Aromatase is responsible for the conversion of androgen into oestradiol. Male removal from a socially stable group resulted in rapid and dramatic (>= 200%) increases in aggression in the dominant female, which will become male usually 7-10 days later. These dominant females and recently sex-changed individuals had lower bAA but similar gonadal aromatase activity (gAA) compared to control females, while established males had lower bAA than all groups and lower gAA than all groups except dominant females. Within hours of male removal, dominant females' aggressive behaviour was inversely related to bAA but not gAA. These results are novel because they are the first to: (i) demonstrate socially induced decreases in bAA levels corresponding with increased aggression, (ii) identify this process as a possible neurochemical mechanism regulating the induction of behavioural, and subsequently gonadal, sex change and (iii) show differential regulation of bAA versus gAA resulting from social manipulations. Combined with other studies, this suggests that aromatase activity may modulate fast changes in vertebrate social behaviour.