Effect of acute stress on the pituitary gland: endocrine gland blood flow.
Effect of acute stress on the pituitary gland: endocrine gland blood flow.
复制标题
急性应激对垂体的影响：内分泌腺血流。
作者：
H. Goldman
采用铷86法测定雌性Wistar大鼠垂体前叶、垂体后叶、肾上腺、甲状腺和正中隆起的最小血流量。最大的变化发生在血流量2.5分钟后，发病的1分钟乙醚应力。此时，垂体前叶流量增加了约40%，甲状腺流量增加了一倍。其他腺体的流量不变。无应激肾上腺切除大鼠腺垂体血流量显着升高;应激再次增加流量约45%。在这些动物中，垂体后叶对压力的反应是流量增加67%。然而，甲状腺流量未能增加。阻断剂量的氢化可的松在完整的大鼠并没有改变休息垂体前叶血流量，也没有抑制增加的流量反应的压力。肾上腺切除术后腺垂体流量增加似乎是由腺体代谢自动调节。然而，额外的快速增加后，压力表明，一个V…
The minimal blood flows through the anterior and posterior pituitary, adrenal and thyroid glands and median eminence were determined in female Wistar rats using a rubidium86 method. Maximum change in blood flow occurred 2.5 min after the onset of a 1-min ether stress. At this time anterior pituitary flow had increased by about 40% and thyroid flow had doubled. Flows for the other glands were unchanged. Adenohypophysial blood flow in unstressed adrenalectomized rats was significantly elevated; stress again increased the flow by about 45%. In these animals, the posterior pituitary responded to stress with a 67% increase in flow. However, thyroid flow failed to increase. A blocking dose of hydrocortisone in intact rats did not alter the resting anterior pituitary blood flow, nor did it suppress the increased flow response to stress. The increased adenohypophysial flow after adrenalectomy appears to be autoregulated by glandular metabolism. However, the additional rapid increase after stress suggests that a v...