THE STRUCTURE OF THE SINUS WALL OF THE LYMPH-NODE RELATIVE TO ITS ENDOCYTIC PROPERTIES AND TRANSMURAL CELL PASSAGE
THE STRUCTURE OF THE SINUS WALL OF THE LYMPH-NODE RELATIVE TO ITS ENDOCYTIC PROPERTIES AND TRANSMURAL CELL PASSAGE
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DOI：
10.1002/aja.1001570304
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发表时间：
1980-01-01
影响因子：
--
通讯作者：
DEBRUYN, PPH
中科院分区：
文献类型：
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作者：
FARR, AG;CHO, Y;DEBRUYN, PPH
排列在淋巴结淋巴窦内的细胞的内部结构包括用于内吞物质的摄取和细胞内处置的大刚毛包被的囊泡、转移小管和囊泡细胞器。窦的衬里细胞以与骨髓窦内皮从血液中摄取颗粒相同的方式从淋巴中吞噬颗粒物质，并且在这方面与骨髓窦的内皮衬里相似。大鼠淋巴结中淋巴窦壁的透射和扫描电子显微镜检查显示，淋巴窦壁是连续的，并且没有永久性孔，使得淋巴结中窦外和窦内隔室之间能够自由连通。迁移淋巴细胞在细胞内穿过淋巴窦壁，即，通过形成一个暂时的迁移孔，穿过衬里细胞的身体，在细胞到达窦腔后，该孔关闭。在透壁位置有巨噬细胞的零星聚集。他们的行动方向不明。
The internal structure of cells lining the lymphatic sinus of the lymph node includes large bristle-coated vesicles, transfer tubule and vesicular organelles for the uptake and intracellular disposition of endocytosed material. Lining cells of the sinuses phagocytose particulate material from lymph in the same manner as the sinusoidal endothelium of the bone marrow takes up particulates from the blood and are similar in this respect to the endothelial lining of the bone marrow sinusoids. Transmission and scanning electron microscopic examination of the lymphatic sinus wall in rat lymph nodes show that the walls of the lymphatic sinuses are continuous and do not have permanent apertures allowing free communication between the extrasinusoidal and intrasinusoidal compartments in the lymph node. Migrating lymphocytes cross the lymphatic sinus wall intracellularly, ie., through the body of the lining cell, by making a temporary migration pore, which closes after the cell has reached the lumen of the sinus. There are sporadic aggregations of macrophages in transmural positions. Direction of their movement is unknown.