Mutations in context: implications of BRCA testing in diverse populations.
Mutations in context: implications of BRCA testing in diverse populations.
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DOI：
10.1007/s10689-017-0038-2
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发表时间：
2018-10
期刊：
影响因子：
2.2
通讯作者：
Olopade OI
中科院分区：
文献类型：
--
作者：
Felix GES;Zheng Y;Olopade OI
Cancer is a common non-communicable disease worldwide, although it exhibits differential population trends in incidence and mortality rates. The differences relate to population structure, environmental risk factors as well as health system organization. This article discusses the potential impact of genetic testing on population health, focusing in particular on the mutational spectrum of breast cancer susceptibility genes in diverse populations. We identify the need for improved access to, and increased investment in, comprehensive cancer risk assessment and genetic testing as well as cancer control measures that take into account lifestyle, environmental, and social factors in understudied minority groups.
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