ENGRAFTMENT FOLLOWING T-CELL-DEPLETED BONE-MARROW TRANSPLANTATION .3. DIFFERENTIAL-EFFECTS OF INCREASED TOTAL-BODY IRRADIATION ON SEMIALLOGENEIC AND ALLOGENEIC RECIPIENTS
ENGRAFTMENT FOLLOWING T-CELL-DEPLETED BONE-MARROW TRANSPLANTATION .3. DIFFERENTIAL-EFFECTS OF INCREASED TOTAL-BODY IRRADIATION ON SEMIALLOGENEIC AND ALLOGENEIC RECIPIENTS
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DOI：
10.1097/00007890-198805000-00022
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发表时间：
1988-05-01
期刊：
影响因子：
6.2
通讯作者：
MAUCH, P
中科院分区：
文献类型：
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作者：
FERRARA, JLM;MICHAELSON, J;MAUCH, P
分析了三种不同剂量的全身照射（TBI）（1100、1300、1500 cGy）作为T细胞耗尽的C57 BL 6（H-2b）骨髓移植物的半同种异体B6 AF 1（H-2b × H-2a）和同种异体A/J（H-2a）受体的预处理方案。在每组中检查供体红细胞和淋巴细胞的存活和植入。绝大多数接受1100 cGy剂量的同种异体小鼠排斥移植物，导致存活率低（
Three different doses of total-body irradiation (TBI) (1100, 1300, 1500 cGy) have been analyzed as conditioning regimens for semiallogeneic B6AF1 (H-2b.times.H-2a) and allogenic A/J (H-2a) recipients of T cell-depleted C57BL6 (H-2b) bone marrow transplants. Recipient survival and engraftment of both donor erythrocytes and lymphocytes were examined in each group. The large majority of allogeneic mice prepared with 1100 cGy rejected their grafts, which resulted in poor survival (