Evaluation of a multi-element treatment center for early psychosis in the United States.

Evaluation of a multi-element treatment center for early psychosis in the United States.
复制标题

对美国早期精神病多要素治疗中心的评估。

DOI:
10.1007/s00127-011-0467-4
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发表时间:
2012
影响因子:
4.4
通讯作者:
Perkins,DianaO
Perkins,DianaO
中科院分区:
医学2区
文献类型:
--
作者:
Uzenoff,SarahR;Penn,DavidL;Graham,KarenA;Saade,Sylvia;Smith,BarbaraB;Perkins,DianaO

文献摘要

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目的越来越多的研究表明,综合性、阶段性的护理有可能改善早期精神病的临床和功能结局。然而,在美国(US)还没有对这种治疗模式进行评估。这项研究是一个自然的,前瞻性的1年随访的早期精神病队列治疗的第一个美国的多元素treatment centers.MethodsParticipants之一,163个人在外展和支持干预服务(OASIS)诊所,早期精神病的多元素治疗中心治疗。作为常规护理的一部分,每隔6个月收集数据。主要成果包括角色功能和参与工作或school.ResultsOver 1年的治疗过程中,个人经历了显着改善的积极和消极的症状,角色功能,和全球功能。从基线到1年,符合症状缓解和功能缓解标准的个体比例显著增加,上学的个体比例也是如此。也有趋势水平的减少药物滥用。ConclusionsThis study provides preliminary support for the efficacy of comprehensive early intervention services in the US.
PurposeA growing body of research has demonstrated the potential for comprehensive, phase-specific care to improve clinical and functional outcomes in early psychosis. However, there have been no evaluations of such treatment models in the United States (US). This study is a naturalistic, prospective 1-year follow-up of an early psychosis cohort treated in one of the first US-based multi-element treatment centers.MethodsParticipants were 163 individuals treated at the Outreach and Support Intervention Services (OASIS) clinic, a multi-element treatment center for early psychosis. Data were collected as part of routine care at 6-month intervals. Primary outcomes included role functioning and involvement in work or school.ResultsOver the course of 1 year of treatment, individuals experienced significant improvements in positive and negative symptoms, role functioning, and global functioning. The proportion of individuals meeting symptom remission and functional remission criteria increased significantly from baseline to 1 year, as did the proportion of individuals attending school. There were also trend-level reductions in substance abuse.ConclusionsThis study provides preliminary support for the efficacy of comprehensive early intervention services in the US.