Breast Cancer Health Disparities in Hispanics/Latinas.
Breast Cancer Health Disparities in Hispanics/Latinas.
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DOI：
10.1007/s12609-020-00370-3
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发表时间：
2020-09
影响因子：
0.9
通讯作者：
Fejerman L
中科院分区：
文献类型：
--
作者：
Serrano-Gomez SJ;Sanabria-Salas MC;Fejerman L
与非西班牙裔白人女性相比，一些西班牙裔/拉丁裔亚群体的乳腺癌发病率和死亡率较低。然而，研究表明，美国西班牙裔/拉丁裔的乳腺癌特异性死亡率较高。在这篇综述中，我们总结了目前关于西班牙裔/拉丁裔女性乳腺癌发病率和死亡风险相关因素的知识。关联研究提出了多种可能导致人群之间乳腺癌发病率和生存率差异的因素，包括社会经济/社会人口因素、生活方式选择以及护理的获取和质量。关于西班牙裔/拉丁裔总体遗传血统与亚型特异性乳腺癌风险之间关联的报告表明，发病率和亚型分布可能是由于与遗传血统以及种系遗传变异相关的环境和生活方式相关因素的不同暴露造成的。美国的西班牙裔/拉丁裔在癌症研究中的代表性基本上不足。重要的是实施包容性计划，以促进该人群获得医疗服务，并包括针对社区开展关于筛查重要性的教育计划。此外，重要的是继续促进将西班牙裔/拉丁裔纳入基因组研究，以便在所有人类遗传多样性的背景下了解这种疾病的生物学行为。
Breast cancer incidence and mortality rates are lower in some Hispanic/Latino subpopulations compared to Non-Hispanic White women. However, studies suggest that the risk of breast cancer-specific mortality is higher in US Hispanics/Latinas. In this review we summarized current knowledge on factors associated with breast cancer incidence and risk of mortality in women of Hispanic/Latino origin. Associative studies have proposed a multiplicity of factors likely contributing to differences in breast cancer incidence and survival between population groups, including socioeconomic/sociodemographic factors, lifestyle choices as well as access to and quality of care. Reports of association between global genetic ancestry overall as well as subtype-specific breast cancer risk among Hispanic/Latinas suggest that incidence and subtype distribution could result from differential exposure to environmental and lifestyle related factors correlated with genetic ancestry as well as germline genetic variation. Hispanic/Latino in the United States have been largely underrepresented in cancer research. It is important to implement inclusive programs that facilitate the access of this population to health services and that also include education programs for the community on the importance of screening. In addition, it is important to continue promoting the inclusion of Hispanics/Latinos in genomic studies that allow understanding the biological behavior of this disease in the context of all human genetic diversity.
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DOI：
10.1158/1055-9965.epi-15-0293
发表时间：
2015-11
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Chen L;Li CI
通讯作者：
Li CI
影响因子：
45.3
作者：
Biggers, Alana;Shi, Yushu;Neuner, Joan M.
通讯作者：
Neuner, Joan M.
影响因子：
3.8
作者：
Akinyemiju T;Moore JX;Ojesina AI;Waterbor JW;Altekruse SF
通讯作者：
Altekruse SF
DOI：
10.1007/s12032-016-0732-1
发表时间：
2016-02
期刊：
Medical oncology (Northwood, London, England)
影响因子：
--
作者：
Farias AJ;Du XL
通讯作者：
Du XL
影响因子：
3.2
作者：
Dubowitz, Tamara;Subramanian, S. V.;Peterson, Karen E.
通讯作者：
Peterson, Karen E.