Anc1 interacts with the catalytic subunits of the general transcription factors TFIID and TFIIF, the chromatin remodeling complexes RSC and INO80, and the histone acetyltransferase complex NuA3
Anc1 interacts with the catalytic subunits of the general transcription factors TFIID and TFIIF, the chromatin remodeling complexes RSC and INO80, and the histone acetyltransferase complex NuA3
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DOI：
10.1016/j.bbrc.2005.04.158
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发表时间：
2005-07-01
影响因子：
3.1
通讯作者：
Werner, M
中科院分区：
文献类型：
--
作者：
Kabani, M;Michot, K;Werner, M
ANCL蛋白与一般转录因子，染色质重塑复合物和历史修饰酶共纯化，是在酵母中有效转录所必需的。我们在这里表明ANCL与TSM1，TFG1，STH1，INC，80和SAS3相互作用，分别是染色质重塑的一般转录因子TFIID和TFII F的催化亚基RSC和INO80，以及史地H3-乙酰转移酶复合物NUA3。我们表明，生长油半乳糖作为唯一的碳源需要ANCL，并且在诱导后将其募集到GAL1基因的UAS。 （c）2005 Elsevier Inc.保留所有权利。
The Ancl protein co-purifies with general transcription factors, chromatin remodeling complexes, and historic modification enzymes and is required for efficient transcription in yeast. We show here that Ancl interacts with Tsm1, Tfg1, Sth1, Inc,80, and Sas3 that are, respectively, the catalytic subunits of the general transcription factors TFIID and TFII F, of the chromatin remodeling complexes RSC and INO80, and of the historic H3-acetyltransferase complex NuA3. We show that Ancl is required for growth oil galactose as the sole carbon source, and that it is recruited to the UAS of the GAL1 gene after induction. (C) 2005 Elsevier Inc. All rights reserved.