THALAMIC-STIMULATION AND RECORDING IN PATIENTS WITH DEAFFERENTATION AND CENTRAL PAIN
THALAMIC-STIMULATION AND RECORDING IN PATIENTS WITH DEAFFERENTATION AND CENTRAL PAIN
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DOI：
10.1159/000099504
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发表时间：
1989-01-01
影响因子：
1.7
通讯作者：
LENZ, FA
中科院分区：
文献类型：
--
作者：
GORECKI, J;HIRAYAMA, T;LENZ, FA
对39例中枢性或移行性疼痛患者进行丘脑探查。一些患者不止一次或双侧探查；因此，进行了52次勘探。16例采用微电极记录和微刺激。在失神经化的丘脑中，发现了一种中枢性异常痛觉现象，在这种现象中，变态患者在刺激时体验到疼痛，而不是通常的感觉。通过微记录，可以识别出连续发射的不同单元，并将其分为三种类型。在一些患者中，发现丘脑体位图发生改变，这种重组可分为四种类型。
Thalamic exploration was carried out in 39 patients with central or deafferentation pain. Several patients were explored more than once or bilaterally; therefore, 52 explorations were carried out. In 16 cases, microelectrode recording and microstimuIation were employed. In the deafferented thalamus, a phenomenon of central allodynia was identified, in which patients with hyperpathia experience pain on stimulation rather than the usual sensations. With microrecording, a distinct unit firing in bursts can be identified and classified into three types. In several patients, the thalamic somatotopic map is found to be altered, and this reorganization can be classified into four types.