Antiretroviral therapy for control of the HIV-associated tuberculosis epidemic in resource-limited settings.

Antiretroviral therapy for control of the HIV-associated tuberculosis epidemic in resource-limited settings.
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DOI:
10.1016/j.ccm.2009.08.010
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发表时间:
2009-12
影响因子:
5.7
通讯作者:
Wood R
Wood R
中科院分区:
医学3区
文献类型:
--
作者:
Lawn SD;Kranzer K;Wood R

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过去几年中,在对结核病患者进行艾滋病毒检测和扩大抗逆转录病毒治疗方面取得了巨大进展。据估计,到2007年底,在资源有限的环境中,有300多万人已开始抗逆转录病毒治疗,其中200万人在撒哈拉以南非洲。然而,对于这种大规模的公共卫生干预将对与艾滋病毒相关的结核病流行产生何种影响,或者如何利用抗逆转录病毒疗法来最好地控制结核病,人们知之甚少。本文对这些问题进行了深入的回顾。
Great progress has been made over the past few years in HIV testing in patients who have tuberculosis (TB) and in the scale-up of antiretroviral therapy. More than 3 million people in resource-limited settings were estimated to have started antiretroviral therapy by the end of 2007 and 2 million of these were in sub-Saharan Africa. However, little is known about what impact this massive public health intervention will have on the HIV-associated TB epidemic or how antiretroviral therapy might be used to best effect TB control. This article provides an in-depth review of these issues.
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