[99m-Tc-MIBI SPECT parathyroid gland scintigraphy for the preoperative localization of small parathyroid gland adenomas].
[99m-Tc-MIBI SPECT parathyroid gland scintigraphy for the preoperative localization of small parathyroid gland adenomas].
复制标题
99m-Tc-MIBI SPECT 甲状旁腺闪烁显像术用于甲状旁腺小腺瘤的术前定位。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
H. Schicha
中科院分区：
文献类型：
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作者：
D. Moka;E. Voth;A. Larena;H. Schicha
目标
本研究旨在探讨99mTC-MIBI SPECT显像在小型甲状旁腺腺瘤(PTA)术前侧位定位中的应用价值。
方法
对25例确诊为原发性甲状旁腺功能亢进症的患者(男8例，女17例，平均年龄63±13岁)行术前超声检查。在甲状腺检查排除放射性核素积聚的甲状腺腺瘤后，20分钟采集平面和断层图像。120min。静脉注射后。使用3头伽马相机(Picker Prism 3000)注射740MBq 99mTC-MIBI。前10名患者在2天内额外接受了201Tl/99mTc减影核素扫描。
结果
所有患者均有小而孤立的PTA(<；1g)。~(201)Tl/~(99m)Tc减影核素显像(n=10)的灵敏度仅为50%。平面MIBI-核素显像可定位PTA 18例(敏感度72%)。使用SPECT技术和3D显示(体积再现重新投影)，灵敏度提高了96%。
结论
与仅显示低灵敏度的201Tl/99mTC减影显像相比，99mTC-MIBI断层显像能可靠地显示小PTA的侧方位置。这种方法为外科医生提供了进行单侧甲状旁腺切除术的可能性。
AIM
It was the of this study to assess the value of the 99mTc-MIBI scintigraphy in SPECT technique in the preoperative lateral location of small parathyroid adenoma (PTA).
METHODS
25 consecutive patients (8 male, 17 female, mean age 63 +/- 13 years) with the established diagnosis of primary hyperparathyroidism and non-diagnostic ultrasonography were scanned preoperatively. After a thyroid examination to exclude radionuclide accumulating thyroid adenoma, planar and tomographic images were acquired 20 min. and 120 min. after i.v. injection of 740 MBq 99mTc-MIBI using a 3 head gamma camera (Picker Prism 3000). The first 10 patients underwent an additional 201Tl/99mTc subtraction scintigraphy in a 2 days protocol.
RESULTS
All patients had small, solitary PTA (< 1 g). 201Tl/99mTc subtraction scintigraphy (n = 10) showed only a sensitivity of 50%. Using planar MIBI-scintigraphy lateral location of PTA was possible in 18 cases (sensitivity: 72%). There was an increase in sensitivity up to 96% using the SPECT technique and the 3D display (volume-rendered reprojection).
CONCLUSION
In contrast to 201Tl/99mTc subtraction scintigraphy, which showed only a low sensitivity, a reliable lateral location of small PTA was obtained using the tomographic 99mTc-MIBI scintigraphy. This method offers e.g. the possibility for the surgeon to perform an unilateral parathyroidectomy.