Periodontal Status and Metabolic Syndrome in Middle-Aged Japanese
Periodontal Status and Metabolic Syndrome in Middle-Aged Japanese
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DOI：
10.1902/jop.2012.110605
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发表时间：
2012-11-01
影响因子：
4.3
通讯作者：
Yamashita, Yoshihisa
中科院分区：
文献类型：
--
作者：
Fukui, Nao;Shimazaki, Yoshihiro;Yamashita, Yoshihisa
背景：代谢综合征（MetS）增加了各种生活方式相关疾病的风险。虽然一些研究已经报道了牙周状况和代谢综合征之间的显着关系，很少有信息存在牙周健康状况和代谢综合征之间的关系的性质。方法：进行全面的健康检查的6,421名日本人（年龄34至77岁）。对MetS的5个组分（肥胖、高血压、低高密度脂蛋白胆固醇、高甘油三酯血症和高血糖）进行了评估，并且具有≥ 3个阳性组分的个体被定义为患有MetS。牙周参数为牙周探诊深度（PD）和临床附着水平（CAL），每个参数分为3类（无/轻度：≥ 6 mm）。在以PD和CAL作为自变量的多变量logistic回归分析中，重度PD和重度CAL或中度PD和中度CAL的个体发生MetS的优势比显著更高，但无重度PD的重度CAL与MetS无显著相关性。这项研究的结果表明，牙周状况，特别是在个人怀疑有未经治疗的牙周感染表明>= 4毫米PD，与代谢综合征显著相关牙周病学杂志2012;83：1363-1371。
Background: Metabolic syndrome (MetS) increases the risk of various lifestyle-related diseases. Although some studies have reported a significant relationship between periodontal status and MetS, little information exists about the nature of the relationship between periodontal health status and MetS.Methods: Comprehensive health examinations of 6,421 Japanese individuals (aged 34 to 77 years) were performed. Five components (obesity, high blood pressure, low high-density lipoprotein cholesterol, hypertriglyceridemia, and high plasma glucose) of MetS were evaluated, and individuals with >= 3 positive components were defined as having MetS. The periodontal parameters were periodontal probing depth (PD) and clinical attachment level (CAL), and each parameter was divided into three categories (none/mild: = 6 mm).Results: When PD and CAL were analyzed separately in multivariate models, both parameters were significantly associated with MetS. In a multivariate logistic regression analysis using a combination of PD and CAL as an independent variable, individuals with severe PD and severe CAL or with moderate PD and moderate CAL had significantly higher odds ratios for MetS, but severe CAL without severe PD was not significantly associated with MetS.Conclusion: The results of this study suggest that periodontal status, particularly in individuals suspected to have untreated periodontal infection indicated by >= 4 mm PD, is significantly associated with MetS. J Periodontol 2012;83:1363-1371.