Adherence to Mediterranean diet and risk of developing diabetes:: prospective cohort study
Adherence to Mediterranean diet and risk of developing diabetes:: prospective cohort study
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DOI：
10.1136/bmj.39561.501007.be
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发表时间：
2008-06-14
影响因子：
105.7
通讯作者：
Bes-Rastrollo, M.
中科院分区：
文献类型：
--
作者：
Martinez-Gonzalez, M. A.;de la Fuente-Arrillaga, C.;Bes-Rastrollo, M.
目的探讨地中海饮食与糖尿病发病率的关系。设计前瞻性队列研究，调整性别、年龄、大学教育年限、总能量摄入量、体重指数、体力活动、久坐习惯、吸烟、糖尿病家族史和个人高血压病史等因素后的相对风险。参与者13380名西班牙大学毕业生在基线水平上没有糖尿病，平均随访时间为4.4年。主要结果衡量饮食习惯，在基线水平上用有效的136项食物频率问卷进行评估，并按9分指数进行评分。通过医学报告和向那些自我报告医生在随访期间新诊断为糖尿病的人发布的额外详细问卷，确认了新的糖尿病病例。结果坚持地中海饮食的参与者患糖尿病的风险较低。经性别和年龄调整后，与低依从性(评分)相比，中等依从性(评分3-6)者的发病率比为0.41(95%可信区间0.19-0.87)，最高依从性(评分7-9)者的发病率比为0.17(0.04-0.75
Objective To assess the relation between adherence to a Mediterranean diet and the incidence of diabetes among initially healthy participants.Design Prospective cohort study with estimates of relative risk adjusted for sex, age, years of university education, total energy intake, body mass index, physical activity, sedentary habits, smoking, family history of diabetes, and personal history of hypertension.Setting Spanish university department. Participants 13 380 Spanish university graduates without diabetes at baseline followed up fora median of 4.4 years.Main outcome measures Dietary habits assessed at baseline with a validated 136 item food frequency questionnaire and scored on a nine point index. New cases of diabetes confirmed through medical reports and an additional detailed questionnaire posted to those who self reported a new diagnosis of diabetes by a doctor during follow-up. Confirmed cases of type 2 diabetes.Results Participants who adhered closely to a Mediterranean diet had a lower risk of diabetes. The incidence rate ratios adjusted for sex and age were 0.41 (95% confidence interval 0.19 to 0.87) for those with moderate adherence (score 3-6) and 0.17 (0.04 to 0.75) for those with the highest adherence (score 7-9) compared with those with low adherence (score