- Feasibility, clinical efficacy, and wellbeing outcomes of an online singing intervention for postnatal depression in the UK: SHAPER-PNDO, a single-arm clinical trial
- Feasibility, clinical efficacy, and wellbeing outcomes of an online singing intervention for postnatal depression in the UK: SHAPER-PNDO, a single-arm clinical trial
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- 英国在线歌唱干预治疗产后抑郁症的可行性、临床疗效和健康结果：SHAPER-PNDO，一项单臂临床试验
DOI：
10.1016/j.psyneuen.2023.106910
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发表时间：
2024
影响因子：
3.7
通讯作者：
Bind R
中科院分区：
文献类型：
--
作者：
Bind R
背景产后抑郁症（PND）影响了超过12%的母亲，在COVID-19大流行期间，这一数字有所上升。唱歌小组可以支持患有PND的母亲;然而，在线提供的小组唱歌从未被评估过。SHAPER-PNDO是一项单臂临床试验，评估了为期六周的在线版本的母亲呼吸旋律（M4 M）歌唱干预的可行性，临床疗效和健康结果，该干预是为COVID-19封锁期间患有PND的母亲开发的。在英国，共有37名母亲通过社交媒体和初级保健招募。以患者为中心的主要临床结局是爱丁堡产后抑郁量表（EPDS）评分从基线至干预结束（第6周）的变化;在第3、16和32周完成随访评估。收集的其他措施包括状态-特质焦虑量表（STAI），感知压力量表（PSS）和国家统计局幸福量表（ONS）。母亲是合格的，如果他们得分至少10的基线EPDS.Results87%的37名招募的母亲完成了研究，参加，平均，5 6组唱歌会议。关于以患者为中心的结局，在治疗结束时，母亲经历了：抑郁症的显著减少（EPDS，16.6±3.7至11.2±5.3，95% CI [0.79，1.65]），焦虑（STAI-S，48.4±27.1至41.7±26.8，95% CI [4.96，17.65]）和应力（PSS，29.0±5.7至19.7±5.3，95% CI [1.33，7.07]）;此外，生活满意度也有显著提高（ONS，50.5±23.0至72.8±11.7，95% CI [- 39.86，-4.64]）和健康感觉（ONS，51.7±30.4 ~ 78.6±15.1，95%CI [-52.79，-0.85]）。此外，M4 M在线支持新妈妈的心理健康和幸福经历PND，特别是当障碍的人治疗是present.FundingThe形状PNDO研究是由惠康信托基金资助。Bind博士由生物医学研究理事会和南伦敦和Maudsley信托基金资助。
BackgroundPostnatal depression (PND) affects over 12% of mothers, with numbers rising during the COVID-19 pandemic. Singing groups can support mothers with PND; however, the online delivery of group singing has never been evaluated. SHAPER-PNDO, a single-arm clinical trial, evaluated the feasibility, clinical efficacy, and wellbeing outcomes of a six-week online version of Breathe Melodies for Mums (M4M) singing intervention developed for mothers with PND during COVID-19 lockdowns.MethodsThe primary objective of this study was to assess the feasibility and acceptability of a group online singing intervention for new mothers with postnatal depression. In total, 37 mothers were recruited via social media and primary care in the UK. The primary patient-centred clinical outcome was change in Edinburgh Postnatal Depression Scale (EPDS) score from baseline to end-of-intervention (week 6); and follow-up assessments were completed at weeks 3, 16, and 32. Additional measures collected included State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS), and Office for National Statistics Wellbeing Scale (ONS). Mothers were eligible if they scored at least 10 on the baseline EPDS.Results87% of the 37 recruited mothers completed the study, attending, on average, 5 of the 6 group singing sessions. With regard to patient-centred outcomes, at end-of-treatment, mothers experienced: significant reductions in depression (EPDS, 16.6±3.7 to 11.2±5.3, 95% CI [0.79,1.65]), anxiety (STAI-S, 48.4±27.1 to 41.7±26.8, 95% CI [4.96, 17.65]) and stress (PSS, 29.0±5.7 to 19.7±5.3, 95% CI [1.33, 7.07]); and, furthermore, significant improvements in life satisfaction (ONS, 50.5±23.0 to 72.8±11.7, 95% CI [- 39.86, -4.64]) and feelings of worthwhileness (ONS, 51.7±30.4 to 78.6±15.1, 95% CI [-52.79, -0.85]).ConclusionsM4M online was feasible and acceptable to mothers who partook in the program. Furthermore, M4M online supports the mental health and wellbeing of new mothers experiencing PND, especially when barriers to in-person treatment are present.FundingThe SHAPER-PNDO study was supported by a grant from the Wellcome Trust. Dr Bind is funded by the Biomedical Research Council and the South London and Maudsley Trust.