Genome sequences of Phytophthora enable translational plant disease management and accelerate research
Genome sequences of Phytophthora enable translational plant disease management and accelerate research
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DOI：
10.1080/07060661.2012.664568
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发表时间：
2012-01-01
影响因子：
2
通讯作者：
Gruenwald, Niklaus J.
中科院分区：
文献类型：
--
作者：
Gruenwald, Niklaus J.
全基因组和部分基因组序列正以越来越快的速度变得可用。对于许多植物病原体系统，我们正在进入基因组重测序的时代。第一批疫霉基因组，即拉氏疫霉和大豆疫霉，于2004年问世，随后不久又于2006年问世了寄生疫霉。全基因组序列的可用性在几个领域提供了快速和直接的进步，也产生了许多实际应用和关键的新见解。比较基因组数据的可用性促进了新效应类的发现，如RxLR-dEER和皱纹效应家族。基因组数据还使群体基因组方法的分子标记得以发展，为疫霉菌物种和分支的进化史提供了重要的新见解。在卵菌研究界的共同努力下，通过比较基因组方法取得的一些进展的例子被回顾。
Whole and partial genome sequences are becoming available at an ever-increasing pace. For many plant pathogen systems, we are moving into the era of genome resequencing. The first Phytophthora genomes, P. ramorum and P. sojae, became available in 2004, followed shortly by P. infestans in 2006. Availability of whole genome sequences has provided rapid and immediate advances in several areas also resulting in many practical applications and critical new insights. Availability of comparative genome data facilitated discovery of new classes of effectors, such as the RxLR-dEER and crinkler effector families. Genome data also enabled development of molecular markers for population genomic approaches that provided critical new insights into the evolutionary history of species and clades of Phytophthora. Several select examples of advances resulting from comparative genomic approaches in a concerted effort of the Oomycete research community are reviewed.