Ring-expanded analogues of natural oxetanocin: (+) and (-) hydroxymethyl isodideoxyadenosine.
Ring-expanded analogues of natural oxetanocin: (+) and (-) hydroxymethyl isodideoxyadenosine.
复制标题
天然奥塞塔辛的扩环类似物：( ) 和 (-) 羟甲基异二脱氧腺苷。
DOI：
10.1081/ncn-200060036
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Nair,Vasu
中科院分区：
文献类型：
--
作者：
Chun,Byoung-Kwon;Vadakkan,JeanJohn;Nair,Vasu
New enantiomeric isonucleoside analogues related to natural oxetanocin have been synthesized from D-glucosamine and D-glucose. The structures of the target compounds were confirmed by NMR, HRMS, UV, single crystal X-ray, and optical rotation data. Stability studies with respect to purine nucleoside phosphorylase and adenosine deaminase show that these compounds are not substrates. Antiviral results are discussed.
