Skin morphology of the Clawn miniature pig.
Skin morphology of the Clawn miniature pig.
复制标题
爪型小型猪的皮肤形态。
DOI：
10.1538/expanim.56.369
复制
发表时间：
2007
影响因子：
2.4
通讯作者：
Shusaku Suzuki
中科院分区：
文献类型：
--
作者：
A. Yabuki;R. Kamimura;Kentaro Setoyama;J. Tottori;K. Taniguchi;M. Matsumoto;Shusaku Suzuki
本文研究了爪型小型猪（CMP）腋窝、大腿内侧、背部和腰部的皮肤形态。表皮的平均厚度（不包括角膜层）、构成表皮的角质形成细胞的平均层数和角质形成细胞的平均高度通过形态测定进行评估。当在光学显微镜下观察时，CMP的皮肤类似于人的皮肤。在形态学上，CMP的背部和腰部的皮肤最类似于人类皮肤。电子显微镜观察发现稀疏，但典型的Birbeck颗粒在表皮朗格汉斯细胞的CMP。本研究的结果表明，CMP皮肤作为人体皮肤的模型是潜在有用的。
Skin morphology of the Clawn miniature pig (CMP) was investigated at the axilla, medial thigh, back and loin. The mean thickness of the epidermis (excluding the corneal layer), the mean number of layers of keratinocytes comprising the epidermis and the mean height of keratinocytes were assessed morphometrically. When observed under a light microscope, the skin of the CMP resembled human skin. Morphometrically, skin from the back and loin of the CMP most resembles human skin. Electron microscopic observations revealed sparse but typical Birbeck granules in the epidermal Langerhans cells of the CMP. The results of the present study indicate that CMP skin is potentially useful as a model for human skin.