Increasing Incidence of Melanoma Among Young Adults: An Epidemiological Study in Olmsted County, Minnesota
Increasing Incidence of Melanoma Among Young Adults: An Epidemiological Study in Olmsted County, Minnesota
复制标题
DOI：
10.1016/j.mayocp.2012.01.010
复制
发表时间：
2012-04-01
影响因子：
8.9
通讯作者：
Gibson, Lawrence E.
中科院分区：
文献类型：
--
作者：
Reed, Kurtis B.;Brewer, Jerry D.;Gibson, Lawrence E.
目的：确定青少年皮肤黑色素瘤发病率随时间的变化。患者和方法：利用罗彻斯特流行病学项目数据，我们确定了明尼苏达州奥姆斯特县1970年1月1日至2009年12月31日期间首次被诊断为终生黑色素瘤的18至39岁患者。结果：从1970年到2009年，年轻女性的黑色素瘤发病率增加了8倍，年轻男性的黑色素瘤发病率增加了4倍。随着时间的推移，总体和特定疾病的生存率似乎有所改善；将确诊年份与死亡率进行比较的风险比分别为0.92和0.91。结论：年轻人中皮肤黑色素瘤的发病率正在迅速上升，尤其是在女性中。有必要继续密切监测这一高危人群。(C)2012年梅奥医学教育和研究基金会广场梅奥临床程序。2012年；87(4)：328-334
Objective: To identify the change in the incidence of cutaneous melanoma over time among young adults.Patients and Methods: Using Rochester Epidemiology Project data, we identified patients aged 18 to 39 years who had a first lifetime diagnosis of melanoma from January 1, 1970, through December 31, 2009, in Olmsted County, Minnesota. Demographic and clinical information, including survival, was abstracted, and estimates of the incidence of melanoma and overall and disease-specific survival were generated.Results: From 1970 to 2009, the incidence of melanoma increased by 8-fold among young women and 4-fold among young men. Overall and disease-specific survival seemed to improve over time; hazard ratios comparing year of diagnosis with mortality were 0.92 and 0.91, respectively.Conclusion: The incidence of cutaneous melanoma among young adults is rapidly increasing, especially among women. Continued close monitoring of this high-risk population is necessary. (C) 2012 Mayo Foundation for Medical Education and Research square Mayo Clin Proc. 2012;87(4):328-334