The DET1-COP1-HY5 Pathway Constitutes a Multipurpose Signaling Module Regulating Plant Photomorphogenesis and Thermomorphogenesis
The DET1-COP1-HY5 Pathway Constitutes a Multipurpose Signaling Module Regulating Plant Photomorphogenesis and Thermomorphogenesis
复制标题
DOI：
10.1016/j.celrep.2014.11.043
复制
发表时间：
2014-12-24
期刊：
影响因子：
8.8
通讯作者：
Quint, Marcel
中科院分区：
文献类型：
--
作者：
Delker, Carolin;Sonntag, Louisa;Quint, Marcel
发育可塑性使植物能够通过调整其枝条结构来对升高的环境温度做出反应。在细胞水平上，碱性-螺旋-环-螺旋（bHLH）转录因子光敏色素相互作用因子4（PIF 4）通过激活激素模块（反过来调节生长）协调这种反应。除了未知的温度感应机制外，目前还不清楚温度如何调节PIF 4活性。使用正向遗传方法在拟南芥中，我们提出了广泛的遗传证据表明，DET 1（DET 1）-组成型光形态发生1（COP 1）-延长下胚轴5（HY 5）-依赖的光形态发生途径转录调节PIF 4协调幼苗生长响应温度升高。我们的研究结果表明，两个最普遍的环境线索，光和温度，共享一个更大的信号组件比以前假设的。与动物胚胎模式中的工具箱概念类似，多用途信号模块可能已经在植物中进化，将各种环境刺激转化为适应性生长过程。
Developmental plasticity enables plants to respond to elevated ambient temperatures by adapting their shoot architecture. On the cellular level, the basic-helix-loop-helix (bHLH) transcription factor PHYTOCHROME INTERACTING FACTOR 4 (PIF4) coordinates this response by activating hormonal modules that in turn regulate growth. In addition to an unknown temperature-sensing mechanism, it is currently not understood how temperature regulates PIF4 activity. Using a forward genetic approach in Arabidopsis thaliana, we present extensive genetic evidence demonstrating that the DE-ETIOLATED 1 (DET1)-CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1)-ELONGATED HYPOCOTYL 5 (HY5)-dependent photomorphogenesis pathway transcriptionally regulates PIF4 to coordinate seedling growth in response to elevated temperature. Our findings demonstrate that two of the most prevalent environmental cues, light and temperature, share a much larger set of signaling components than previously assumed. Similar to the toolbox concept in animal embryonic patterning, multipurpose signaling modules might have evolved in plants to translate various environmental stimuli into adaptational growth processes.