Magnetic Resonance Fingerprinting - a promising new approach to obtain standardized imaging biomarkers from MRI.
Magnetic Resonance Fingerprinting - a promising new approach to obtain standardized imaging biomarkers from MRI.
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DOI：
10.1007/s13244-015-0403-3
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发表时间：
2015-04
影响因子：
4.7
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中科院分区：
文献类型：
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目前常规的MRI检查依赖于获取具有混合(磁性)组织属性的对比度“加权”的定性图像。最近，一种新的方法被引入，即磁共振指纹(MRF)，它在数据采集、后处理和可视化方面有着完全不同的方法。MRF不是使用重复的、连续的数据采集来表征感兴趣的各个参数，而是使用伪随机化采集，该采集使得来自不同组织的信号具有同时是所研究的多种材料特性的函数的独特的信号演变或“指纹”。采集后的处理涉及模式识别算法，以将指纹与预测信号演变的预定义词典进行匹配。然后可以将这些转换成感兴趣的磁参数的定量图。磁共振指纹(MRF)是一种理论上可以应用于大多数传统定性MRI方法的技术，并以获取真正定量的组织测量取而代之。因此，MRF有望比传统MRI更准确和更可重复性，并应改善多中心研究，并显著减少进行诊断成像时的读者偏差。关键点·磁共振指纹(MRF)是一种新的数据采集、后处理和可视化方法。·MRF提供高精度的T1、T2、质子密度、扩散的定量地图。·MRF可以提供高重复性的多参数成像，并具有多中心/多供应商研究的高潜力。
Current routine MRI examinations rely on the acquisition of qualitative images that have a contrast “weighted” for a mixture of (magnetic) tissue properties. Recently, a novel approach was introduced, namely MR Fingerprinting (MRF) with a completely different approach to data acquisition, post-processing and visualization. Instead of using a repeated, serial acquisition of data for the characterization of individual parameters of interest, MRF uses a pseudo randomized acquisition that causes the signals from different tissues to have a unique signal evolution or ‘fingerprint’ that is simultaneously a function of the multiple material properties under investigation. The processing after acquisition involves a pattern recognition algorithm to match the fingerprints to a predefined dictionary of predicted signal evolutions. These can then be translated into quantitative maps of the magnetic parameters of interest. MR Fingerprinting (MRF) is a technique that could theoretically be applied to most traditional qualitative MRI methods and replaces them with acquisition of truly quantitative tissue measures. MRF is, thereby, expected to be much more accurate and reproducible than traditional MRI and should improve multi-center studies and significantly reduce reader bias when diagnostic imaging is performed. Key Points • MR fingerprinting (MRF) is a new approach to data acquisition, post-processing and visualization. • MRF provides highly accurate quantitative maps of T1, T2, proton density, diffusion. • MRF may offer multiparametric imaging with high reproducibility, and high potential for multicenter/ multivendor studies.