APPLICATION OF MATHEMATICAL REMOVAL OF POSITRON RANGE BLURRING IN POSITRON EMISSION TOMOGRAPHY
APPLICATION OF MATHEMATICAL REMOVAL OF POSITRON RANGE BLURRING IN POSITRON EMISSION TOMOGRAPHY
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DOI：
10.1109/23.57379
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发表时间：
1990-06-01
影响因子：
1.8
通讯作者：
UBER, D
中科院分区：
文献类型：
--
作者：
HABER, SF;DERENZO, SE;UBER, D
正电子在组织中的范围是正电子发射断层成像所能达到的最终空间分辨率的一个重要限制。在这项工作中，傅里叶反卷积技术被用来消除由Donner 600晶体正电子断层扫描仪拍摄的图像中的距离模糊。使用体模数据，作者发现/sup 68/Ga和/sup 82/Rb的图像质量和半高宽都有显著改善。这些都得到了成功的修正，使得图像和半高宽几乎与/sup 18/F的图像和半高宽匹配，后者的正电子范围可以忽略不计。然而，去卷积过程增加了统计噪声，恢复层析成像的全空间分辨率是不现实的。
The range of positrons in tissue is an important limitation to the ultimate spatial resolution achievable in positron emission tomography. In this work, a Fourier deconvolution technique is applied to remove range blurring in images taken by the Donner 600-crystal positron tomograph. Using phantom data, the authors found significant improvement in the image quality and the FWHM for both /sup 68/Ga and /sup 82/Rb. These were successfully corrected so that the images and FWHM almost matched those of /sup 18/F, which has negligible positron range. However, statistical noise was increased by the deconvolution process and it was not practical to recover the full spatial resolution of the tomograph.<>