Classification of types of intraductal papillary-mucinous neoplasm of the pancreas:: a consensus study
Classification of types of intraductal papillary-mucinous neoplasm of the pancreas:: a consensus study
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DOI：
10.1007/s00428-005-0039-7
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发表时间：
2005-11-01
期刊：
影响因子：
3.5
通讯作者：
Yonezawa, S
中科院分区：
文献类型：
--
作者：
Furukawa, T;Klöppel, G;Yonezawa, S
自首次报道导管内乳头状粘液性肿瘤（IPMN）以来，已经过去了二十多年，很明显IPMN由一系列具有形态学和免疫组化变异的肿瘤组成。在2003年举行的胰腺前驱病变国际专家会议上，一致认为应建立IPMN亚型的共识分类，以便更详细地分析变异的临床病理学意义。根据我们的经验和文献信息，我们选择了IPMN的代表性组织学实例，并定义了一个共识的命名法和标准，用于将变异体分类为不同的IPMN亚型，包括胃型、肠型、胰胆型和嗜酸细胞型。这些定义可用于进一步分析IPMN变异的临床病理意义。
Now that more than two decades have passed since the first reports of intraductal papillary-mucinous neoplasms (IPMNs), it has become clear that IPMN consists of a spectrum of neoplasms with both morphological and immunohistochemical variations. At a meeting of international experts on pancreatic precursor lesions held in 2003, it was agreed that a consensus classification of IPMN subtypes should be established to enable a more detailed analysis of the clinicopathological significance of the variations. Based on our experience and on information from the literature, we selected representative histological examples of IPMNs and defined a consensus nomenclature and criteria for classifying variants as distinctive IPMN subtypes including gastric type, intestinal type, pancreatobiliary type, and oncocytic type. These definitions can be used for further analyses of the clinicopathological significance of the variations of IPMN.