Adverse changes in fibre type composition of the human masseter versus biceps brachii muscle during aging
Adverse changes in fibre type composition of the human masseter versus biceps brachii muscle during aging
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DOI：
10.1016/s0022-510x(97)00208-6
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发表时间：
1998-01-21
影响因子：
4.4
通讯作者：
Thornell, LE
中科院分区：
文献类型：
--
作者：
Monemi, M;Eriksson, PO;Thornell, LE
用形态学和酶组织化学方法研究了6名老年人（平均年龄74岁）咬肌和肱二头肌的功能不同区域（浅部和深部）的纤维组成。当与以前的数据相比，年轻人，咬肌从老年受试者的I型纤维的比例显着下降，IM和II型纤维类型的增加，伴随着肌纤维萎缩。在老年二头肌中，I型纤维比例和纤维直径没有变化，但IIB型纤维含量显著降低。纤维组成的变化，除了以前的研究结果的功能退化的老咬肌，目前的结果可能反映了年龄相关的退行性和适应性过程中的三叉神经肌肉系统的组合。当与以前的研究结果相比，在年轻的成年人咬肌，它可以得出结论，人类咬肌不同的肢体肌肉在纤维组成和结构反应的肌肉在老化过程中。咬肌和肱二头肌之间的这些差异表明，肌肉在衰老过程中的具体变化可能是由于遗传控制，功能表现和神经和激素的影响差异。(C)1998年Elsevier Science B.V.
The fibre composition of functionally different regions, the superficial and the deep portions, of the human masseter and the biceps brachii muscles of six elderly subjects (mean age 74 years) was studied by morphological and enzyme-histochemical methods. When compared to previous data for young adults, the masseter muscle from elderly subjects showed a significant decrease in the proportion of type I fibres and an increase of type IM and II fibre types, concomitant with muscle fibre atrophy. In the old biceps, there were no changes in the type I fibre proportion and fibre diameter, but a significant decrease in the type IIB fibre content. The present results of changes in fibre composition, in addition to previous findings of functional deterioration of the old masseter, probably reflect a combination of age related degenerative and adaptive processes within the trigeminal neuromuscular system. When compared with previous findings in young adult masseter, it can be concluded that the human masseter muscle differs from limb muscles both in fibre composition and in structural response of the muscle during aging. These differences between the masseter and the biceps brachii muscle suggest muscle specific alterations during aging probably due to differences in genetical control, functional performance and nerve and hormonal influences. (C) 1998 Elsevier Science B.V.