INTERHEMISPHERIC PATHWAYS OF THE HIPPOCAMPAL-FORMATION, PRESUBICULUM, AND ENTORHINAL AND POSTERIOR PARAHIPPOCAMPAL CORTICES IN THE RHESUS-MONKEY - THE STRUCTURE AND ORGANIZATION OF THE HIPPOCAMPAL COMMISSURES
INTERHEMISPHERIC PATHWAYS OF THE HIPPOCAMPAL-FORMATION, PRESUBICULUM, AND ENTORHINAL AND POSTERIOR PARAHIPPOCAMPAL CORTICES IN THE RHESUS-MONKEY - THE STRUCTURE AND ORGANIZATION OF THE HIPPOCAMPAL COMMISSURES
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DOI：
10.1002/cne.902330104
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发表时间：
1985-01-01
影响因子：
2.5
通讯作者：
VANHOESEN, GW
中科院分区：
文献类型：
--
作者：
DEMETER, S;ROSENE, DL;VANHOESEN, GW
用放射自显影技术对29只恒河猴(Macaca Mulatta)的发源于海马结构、穹隆系统的丘脑前叶、内嗅皮质和后皮质的大脑半球间通路进行了研究。结果表明，交叉纤维被分成3个连续的体系。海马腹连合位于穹隆下器和室间孔附近的穹隆体部和穹隆前柱之间的交界处；它是由在海马体结构最前部(钩和膝部)发出的轴突形成的。海马背连合位于老茧体体的后端下方，它是由发自海马前副回的悬垂前和内嗅皮层的轴突，以及海马后副回的前皮质和新皮质亚部形成的，但不在海马结构中。海马体交叉位于海马体腹侧联结和背侧联结之间；它是由海马体中的轴突形成的。与终止于对侧皮质区域的海马体腹侧连合和背侧连合的纤维不同，这些交叉纤维终止于对侧隔区。因此，恒河猴的海马腹侧连合和背侧连合似乎与其他哺乳动物中类似的指定结构是同源的。由于这些观察结果也适用于人类海马结构和海马旁区域的大脑半球间纤维，因此在解释穹隆横断对癫痫发作的影响和裂脑研究结果时，必须考虑它们可能的保存，因为穹隆横断可能无法完整地切断海马连合。
The interhemispheric pathways originating in the hippocampal formation, presubiculum, and entorhinal and posterior parahippocampal cortices and coursing through the fornix system were investigated by autoradiographic tracing in 29 rhesus monkeys (Macaca mulatta). The results revealed that crossing fibers are segregated into 3 contiguous systems. A ventral hippocampal commissure lies at the transition between the body and anterior columns of the fornix in the vicinity of the subfornical organ and the interventricular foramina of Monro; it is formed by axons arising in the most anterior (uncal and genual) subdivisions of the hippocampal formation. A dorsal hippocampal commissure lies inferior to the posterior end of the body of the corpus callosum; it is formed by axons arising in the presubiculum and entorhinal cortex of the anterior parahippocampal gyrus and the proisocortical and neocortical subdivisions of the posterior parahippocampal gyrus but not in the hippocampal formation. A hippocampal decussation lies between the ventral hippocampal commissure and dorsal hippocampal commissure; it is formed by axons arising in the body of the hippocampal formation. In contrast to the fibers of the ventral hippocampal commissure and dorsal hippocampal commissure, which terminate in contralateral cortical areas, these decussating fibers terminate in the contralateral septum. Thus, the ventral hippocampal commissure and dorsal hippocampal commissure of the rhesus monkey appear to be homologous to similarly designated structures in other mammals. To the extent that these observations also apply to the interhemispheric fibers of the human hippocampal formation and parahippocampal areas, their possible preservation must be considered when interpreting the effect of callosal transection on seizures and the results of split-brain studies, since callosal transection may fail to sever the hippocampal commissures in their entirety.