Diversity from a Monoculture - Effects of Mutation-on-Copy in a String-Based Artificial Chemistry
Diversity from a Monoculture - Effects of Mutation-on-Copy in a String-Based Artificial Chemistry
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单一栽培的多样性——基于字符串的人工化学中复制突变的影响
DOI：
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
P. Young
中科院分区：
文献类型：
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作者：
S. Hickinbotham;Edward Clark;S. Stepney;T. Clarke;A. Nellis;Mungo Pay;P. Young
我们已经开发出一种人工化学，允许自我维持的分子系统发生突变并展示创新行为。化学中的分子物种由一串符号定义，这些符号既指定了结合亲和力，也指定了反应。我们定义了一种复制酶分子，它可以复制任何其他结合在复制酶上特定区域的分子。分子是在逐个符号的基础上复制的。个别符号偶尔的错误复制形成了我们的突变方案。本文描述了由此产生的进化系统的特征。我们进行了1000次开放式试验，观察到了出人意料的广泛的新兴现象，其中许多与生物系统有相似之处。我们定性地报道了这些现象，并给出了其中最有趣的一个现象的细节：相互依赖的复制酶超循环的出现。
We have developed an artificial chemistry that allows selfmaintaining molecular systems to mutate and exhibit innovative behaviour. The molecular species in the chemistry are defined by strings of symbols that specify both the binding affinity and the reaction. We define a replicase molecule that can copy any other molecule that binds at a particular region on the replicase. Molecules are copied on a symbolby-symbol basis. Occasional mis-copying of an individual symbol forms our mutation scheme. This paper describes the characteristics of the resulting evolutionary system. We ran 1,000 open-ended trials and observed an unexpectedly wide range of emergent phenomena, with many parallels to biological systems. We report these phenomena in qualitative terms, and give details of one of the most interesting among them: the emergence of co-dependent replicase hypercycles.