Biomineralization of calcium carbonate under amino acid carbon dots and its application in bioimaging
Biomineralization of calcium carbonate under amino acid carbon dots and its application in bioimaging
复制标题
DOI：
10.1016/j.matdes.2022.110644
复制
发表时间：
2022-04-13
影响因子：
8.4
通讯作者：
Yu, Lan
中科院分区：
文献类型：
--
作者：
Feng, Zongqi;Yang, Tingyu;Yu, Lan
生物矿化是自然界中普遍存在的现象，生物体可以通过生物矿化制备具有多级有序结构的功能材料。本文受生物矿化的启发，首次建立了氨基酸量子点（ACDs）-CO2-Ca（OH）（2）体系，研究了ACDs存在下CaCO 3的生物矿化过程。ACDs不仅可以控制CaCO 3的形貌和晶型，而且可以在CaCO 3形成过程中掺杂到CaCO 3中，形成具有优异发光性能的ACDs@CaCO3有机-无机杂化荧光材料。同时，通过控制CO2流量和转速也可以控制碳酸钙的形貌和晶型。在此基础上，提出了活性炭存在下碳酸钙生物矿化的可能机理。最后，首次将合成的球形ACDs@CaCO3应用于生物成像领域。我们的工作不仅为多功能生物矿化材料的合成提供了新的仿生方法，为进一步理解生物矿化机理提供了新的见解，而且所合成的新型生物矿化荧光材料在生物成像领域具有巨大的应用潜力。(C)2022作者爱思唯尔有限公司出版
Biomineralization is a common phenomenon in nature, and organisms can prepare functional materials with multi-level ordered structures through biomineralization. Herein, inspired by biomineralization, for the first time, we developed an amino acid quantum dots (ACDs)-CO2-Ca(OH)(2) system to study the biomineralization process of CaCO3 in the presence of ACDs. The ACDs could not only control the morphology and crystal form of CaCO3 but also could be doped into CaCO3 during the formation of CaCO3 to form ACDs@CaCO3 organic-inorganic hybrid fluorescent materials which had excellent luminous ability. Meanwhile, the morphology and crystal form of CaCO3 could also be controlled by controlling the CO2 flow rate and rotation speed. After that, a possible biomineralization mechanism of CaCO3 in the presence of ACDs was proposed. Finally, the synthetic spherical ACDs@CaCO3 were applied to the field of biological imaging for the first time. Our work not only provides new bionic methods for the synthesis of multifunctional biomineralized materials and new insights for further understanding of biomineralization mechanism, but also the synthesized new biomineralization fluorescent materials have great application potential in the field of bioimaging. (C) 2022 The Authors. Published by Elsevier Ltd.