FISSION OF CRYPTS IN SMALL-INTESTINE OF IRRADIATED MOUSE

FISSION OF CRYPTS IN SMALL-INTESTINE OF IRRADIATED MOUSE
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DOI:
10.1111/j.1365-2184.1975.tb01219.x
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发表时间:
1975-01-01
期刊:
CELL AND TISSUE KINETICS
影响因子:
--
通讯作者:
MILLEN, BH
MILLEN, BH
中科院分区:
其他
文献类型:
--
作者:
CAIRNIE, AB;MILLEN, BH

文献摘要

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经过 1600 R 的 X 射线照射后,5 天后测量,小鼠小肠中的隐窝数量减少了 77%。然而,到了 21 天,这个数字稳步增加到接近正常水平。照射后绒毛的数量没有变化。隐窝数量增加的机制是通过已变得比正常情况更大的重新填充的隐窝的出芽和分裂。讨论了密码组织的一些方面。
Following 1600 R of X‐rays there was a reduction in the number of crypts in the small intestine of the mouse by 77% as measured 5 days later. However, by 21 days the number had increased steadily to levels approaching normal. The number of villi did not change following irradiation. The mechanism of increase in crypt number was by budding and fission of repopulated crypts which had become larger than normal. Some aspects of crypt organization are discussed.