Neurocognitive impairment does not predict treatment outcome in obsessive-compulsive disorder
Neurocognitive impairment does not predict treatment outcome in obsessive-compulsive disorder
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DOI：
10.1016/j.brat.2004.06.012
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发表时间：
2005-06-01
影响因子：
4.1
通讯作者：
Hand, I
中科院分区：
文献类型：
--
作者：
Moritz, S;Kloss, M;Hand, I
关于基线神经认知任务表现是否可以预测强迫症（OCD）的治疗反应，存在相互矛盾的证据。在本研究中，我们对 138 名强迫症患者进行了一组执行神经认知测试，这些测试对治疗结果具有假定的敏感性。此外，主观神经认知功能障碍是通过问卷确定的。所有患者都参加了认知行为治疗计划（CBT）。结果显示，反应者 (n = 73) 与无反应者 (n = 65) 在任何参数上都没有差异，除了延迟交替测试的表现下降 (p
There is conflicting evidence pertaining to whether or not neurocognitive task performance at baseline predicts treatment response in obsessive-compulsive disorder (OCD). In the present study, we administered a set of executive neurocognitive tests with a putative sensitivity for treatment outcome to a sample of 138 OCD patients. Additionally, subjective neurocognitive dysfunction was determined via a questionnaire. All patients participated in a cognitive-behavioural treatment program (CBT). Results showed that responders (n = 73) did not differ from non-responders (n = 65) on any of the parameters except for decreased performance on the delayed alternation test (p