Cyanobacteria - a potential source of new biologically active substances
Cyanobacteria - a potential source of new biologically active substances
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DOI：
10.1016/s0168-1656(99)00058-9
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发表时间：
1999-04-30
影响因子：
4.1
通讯作者：
Lindequist, U
中科院分区：
文献类型：
--
作者：
Kreitlow, S;Mundt, S;Lindequist, U
亲水性和亲脂性提取物的12个蓝藻菌株，分离自淡水和咸水，和两个水华，收集在夏季从波罗的海，进行了研究，他们的抗生素活性对7种微生物。对三种革兰氏阴性菌大肠杆菌、奇异变形杆菌和粘质沙雷氏菌以及酵母麦芽糖假丝酵母均无抑制作用。在所有蓝藻样品中，7个物种的提取物抑制了至少一种革兰氏阳性细菌黄色微球菌、金黄色葡萄球菌和枯草芽孢杆菌的生长。在琼脂扩散试验中，黄曲霉菌是最敏感的细菌。特别是，己烷和二氯甲烷提取物显示出抗菌效果。但只有一种水提取物，从天然水华的材料制备，被发现是有效的。(C)1999 Elsevier Science B.V.保留所有权利。
Hydrophilic and lipophilic extracts of twelve cyanobacterial strains, isolated from fresh and brackish water, and two waterblooms, collected during the summer from the Baltic Sea, were investigated for their antibiotic activities against seven microorganisms. No inhibitory effects were found against the three Gram-negative bacteria Escherichia coli, Proteus mirabilis and Serratia marcescens and the yeast Candida maltosa. Of all cyanobacterial samples, extracts from seven species inhibited the growth of at least one of the Gram-positive bacteria Micrococcus flavus, Staphylococcus aureus and Bacillus subtilis. M, flavus proved to be the most sensitive bacterium in the agar diffusion test system. In particular, the hexane and dichlormethane extracts showed antimicrobial effects. But only one water extract, prepared from material of a natural waterbloom, was found to be active. (C) 1999 Elsevier Science B.V. All rights reserved.