Systematic screening allows reduction of adverse antiepileptic drug effects - A randomized trial
Systematic screening allows reduction of adverse antiepileptic drug effects - A randomized trial
复制标题
DOI：
10.1212/wnl.62.1.23
复制
发表时间：
2004-01-13
期刊：
影响因子：
9.9
通讯作者：
Attarian, H
中科院分区：
文献类型：
--
作者：
Gilliam, FG;Fessler, AJ;Attarian, H
目的：确定使用简短的19项自我报告工具不良事件概况（AEP）进行系统筛查的有效性，以减少抗癫痫药物（AED）的不良反应并改善主观健康状况。方法：作者进行了一项前瞻性随机试验，比较使用AEP与不使用AEP的常规护理。62名AEP评分大于或等于45的患者从连续的200名同意的成人癫痫患者中入选。结果如下：接受AEP治疗的患者组AEP评分的平均改善百分比大于常规治疗组（25% vs 5%; p
Objective: To determine the effectiveness of systematic screening with a brief 19-item self-report instrument, the Adverse Events Profile (AEP), to reduce adverse effects of antiepileptic drugs (AEDs) and improve subjective health status. Methods: The authors performed a prospective randomized trial comparing the use of the AEP with usual care without the AEP. Sixty-two patients with an AEP score of greater than or equal to45 were enrolled from a consecutive group of 200 consenting adults with epilepsy. Results: The mean percent improvement in AEP scores was greater in the patient group for which clinicians received the AEP compared with the usual care group (25% vs 5%; p