Quantification of metal trace elements in orthodontic polymeric aligners and retainers by inductively coupled plasma mass spectrometry (ICP-MS)
Quantification of metal trace elements in orthodontic polymeric aligners and retainers by inductively coupled plasma mass spectrometry (ICP-MS)
复制标题
通过电感耦合等离子体质谱 (ICP-MS) 定量正畸聚合物矫正器和保持器中的金属微量元素
DOI：
--
复制
发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Yuxing Bai
中科院分区：
文献类型：
--
作者：
Shang Chen;Song Li;Yuxing Bai
本研究旨在通过动物实验对两种常用的正畸聚合物矫治器和固位体中的金属元素进行评价，并评价其在体内血液中的蓄积情况。分别测定矫治器使用前和佩戴2周后的Al、Ti、V、Cr、Fe、Co、Ni、Cu、Zn、Sn等元素含量。在Wistar大鼠中对口内给药进行建模，并在第28天、第56天和第112天提取静脉血。通过电感耦合等离子体质谱法（ICP-MS）进行痕量元素分析。固位体中检出Al、Ti、V、Cr、Fe、Co、Ni、Cu、Zn，矫治器中检出Al、Ni、Zn、Sn。口腔内佩戴两周后，所识别的元素水平显著降低。聚合物材料中的金属含量既不超过毒性水平，也不超过每日膳食摄入量。在血液中未发现体内蓄积效应。
The aim of this study was to assess the metal elements in two commonly used orthodontic polymeric aligner and retainer, and evaluate the in vivo accumulation in blood by animal experimentation. Elements of Al, Ti, V, Cr, Fe, Co, Ni, Cu, Zn, Sn were quantified in appliances before-use and after two weeks’ wearing. Intraoral usages were modeled in Wistar rats and vein blood was extracted at Day 28, Day 56 and Day 112. Trace elements analyses were conducted by inductively coupled plasma mass spectrometry (ICP-MS). Al, Ti, V, Cr, Fe, Co, Ni, Cu, Zn were detected in retainers, and Al, Ni, Zn and Sn were found in aligners. The identified element levels were significantly decreased after two weeks’ intraorally wearing. The contents of metal in polymeric materials neither exceed the toxic levels nor the daily dietary intake. No in vivo accumulation effects were found in blood..