Memory failures in progressive idiopathic dementia.
Memory failures in progressive idiopathic dementia.
复制标题
进行性特发性痴呆的记忆障碍。
DOI：
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发表时间：
1981
影响因子：
4.6
通讯作者：
Natraj Sitaram
中科院分区：
文献类型：
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作者：
Herbert Weingartner;Walter H. Kaye;S. Smallberg;Michael H. Ebert;J. Gillin;Natraj Sitaram
对14例进行性特发性痴呆（PID）患者和14例正常对照者进行了认知过程的心理测量和实验室测量。患者在韦氏记忆量表（p <0.001）和韦氏成人智力量表（WAIS）操作智商（p <0.01）上的得分显著低于对照组，但在WAIS言语智商或全量表智商以及数字广度测试上均无显著差异。与对照组相比，患者在学习和记忆任务上表现更差。与后者不同的是，患者对分类单词列表的回忆并不比对不相关单词的回忆更好，而且他们并不能始终如一地记住之前回忆过的信息。与对照组相比，患者也不能产生同样多的以给定字母开头的单词（p < .01）或属于给定类别的单词（p < .001）。这些数据被解释为表明，虽然许多智力功能被保留，PID患者无法访问语义记忆中的结构，因此无法有效地编码情节事件，使它们是难忘的。PID和抑郁症的认知功能障碍的差异进行了讨论。
Fourteen patients with progressive idiopathic dementia (PID) were compared with 14 normal controls on psychometric and laboratory measures of cognitive processes. The patients had significantly lower scores than controls did on the Wechsler Memory Scale (p < .001) and the Wechsler Adult Intelligence Scale (WAIS) Performance IQ (p < .01) but not on WAIS Verbal or Full Scale IQ nor on Digit Span tests. The patients performed more poorly on learning and memory tasks than controls. Unlike the latter, the patients' recall of categorized word lists was no better than their recall of unrelated words and they did not consistently remember information that had been previously recalled. Patients also were unable to generate as many words that start with a given letter (p < .01) or that belong to a given category (p < .001) as controls did. The data are interpreted as showing that while many intellectual functions are preserved, PID patients are unable to access structures in semantic memory and therefore fail to effectively encode episodic events so that they are memorable. Differences in cognitive dysfunction in PID and in depression are discussed.