Japanese secular trends in birthweight and the prevalence of low birthweight infants during the last three decades: A population-based study.
Japanese secular trends in birthweight and the prevalence of low birthweight infants during the last three decades: A population-based study.
复制标题
DOI：
10.1038/srep31396
复制
发表时间：
2016-08-09
影响因子：
4.6
通讯作者：
Takeda S
中科院分区：
文献类型：
--
作者：
Takemoto Y;Ota E;Yoneoka D;Mori R;Takeda S
由于低出生体重一直与新生儿和长期健康相关，我们进行了这项流行病学研究，以评估日本在过去30年中平均出生体重的长期趋势和早产/足月低出生体重儿的发生率。我们使用了1979年1月至2010年12月基于人口的出生证明数据。使用线性回归模型分析时间趋势。在研究期间，我们观察到单胎活产儿的平均出生体重显著下降(1979年为3,152 ± 436 g，2010年为3,018 ± 421 g； <； 0.001)，而早产儿/足月低出生体重儿的发生率上升。在研究期间，足月低出生体重儿的比例增加了96.3%(1979年为2.7%，2010年为5.3%)。此外，观察到年轻女性生育的早产儿/低出生体重儿的比例增加(<；35岁与≥35岁)。这些趋势可能与日本女性营养状况的变化以及对怀孕期间体重增加的相对严格的推荐限制有关。了解单胎出生的长期趋势可能会让我们确定相关的风险因素，并减少未来与低出生体重儿相关的社会经济负担。
Since low birthweight has been correlated with both neonatal and long-term health, we performed this epidemiological study to evaluate the Japanese secular trends in mean birthweight and the prevalence of preterm/term low birthweight infants during the last three decades. We used population-based birth certificate data from January 1979 to December 2010. Time trends were analysed using a linear regression model. During the study period, we observed a significant decrease in the mean birthweight for singleton live births (3,152 ± 436 g in 1979 and 3,018 ± 421 g in 2010 p < 0.001) and an increase in the prevalence of preterm/term low birthweight infants. A 96.3% increase in the proportion of term low birthweight infants was observed during the study period (2.7% in 1979 and 5.3% in 2010). In addition, an increased proportion of preterm/low birthweight infants born to younger women was observed (<35 years vs. ≥35 years). These trends may be related to changing patterns in Japanese women’s nutritional status and the relatively strict recommended limit on weight gain during pregnancy. Understanding the long-term trends for singleton births may allow us to identify the associated risk factors and reduce the future socioeconomic burden that is associated with low birthweight infants.