Regioselective Cyclotrimerization of Terminal Alkynes Using a Digermyne
Regioselective Cyclotrimerization of Terminal Alkynes Using a Digermyne
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DOI：
10.1002/anie.201801222
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发表时间：
2018-03-19
影响因子：
16.6
通讯作者：
Tokitoh, Norihiro
中科院分区：
文献类型：
--
作者：
Sugahara, Tomohiro;Guo, Jing-Dong;Tokitoh, Norihiro
中性小分子的催化活化随后形成 C-C 键是增加简单起始材料的复杂性和/或价值的非常重要的方法。报道了一种可分离的二革胺，一种带有 GeGe 键的化合物，可作为末端芳基乙炔环三聚的预催化剂，得到具有绝对区域选择性的相应 1,2,4-三芳基苯。结果表明，定制的主族元素化合物可以催化活化和转化中性有机小分子，并诱导 C-C 键的形成。
The catalytic activation of small neutral molecules followed by the formation of C-C bonds is a highly important method to increase the complexity and/or value of simple starting materials. Reported is an isolable digermyne, a compound with a GeGe bond, which acts as a precatalyst for the cyclotrimerization of terminal arylacetylenes to afford the corresponding 1,2,4-triarylbenzenes with absolute regioselectivity. The results demonstrate that bespoke main-group-element compounds can catalytically activate and transform small neutral organic molecules and induce the formation of C-C bonds.