DISTINCT EXPRESSION OF 2 DROSOPHILA HOMOLOGS OF FIBROBLAST GROWTH-FACTOR RECEPTORS IN IMAGINAL DISKS
DISTINCT EXPRESSION OF 2 DROSOPHILA HOMOLOGS OF FIBROBLAST GROWTH-FACTOR RECEPTORS IN IMAGINAL DISKS
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DOI：
10.1016/0014-5793(93)80494-f
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发表时间：
1993-10-11
期刊：
影响因子：
3.5
通讯作者：
SAIGO, K
中科院分区：
文献类型：
--
作者：
EMORI, Y;SAIGO, K
果蝇同源的FGF受体（DRF1和DRF2）在成虫盘的表达进行了研究。在几个成虫盘中观察到DFR1 mRNA，而DFR2 mRNA未检测到。DFR1在翼和腿盘中的表达发生在可能的成肌细胞中，其模式类似于中胚层基因twist。在眼盘的形态发生沟及其后部和脑的增殖中心周围也检测到mRNA。这些结果表明，DFR1参与了构成成体的中胚层和神经元细胞的发育。
The expression of two Drosophila homologs of FGF receptors (DRF1 and DRF2) in imaginal discs was studied. DFR1 mRNA was observed in several imaginal discs, whereas DFR2 mRNA was not detected. DFR1 expression in the wing and leg discs took place in probable myoblasts in a pattern similar to that of twist, a mesodermal gene. The mRNA was also detected in the morphogenetic furrow and its posterior region of the eye disc and around the proliferation center of the brain. These results suggest that DFR1 is involved in the development of mesodermal and neuronal cells constituting the adult body.