Defining the Microbiome Components (Bacteria, Viruses, Fungi) and Microbiome Geodiversity.
Defining the Microbiome Components (Bacteria, Viruses, Fungi) and Microbiome Geodiversity.
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定义微生物组组成（细菌、病毒、真菌）和微生物组地理多样性。
DOI：
10.1089/sur.2023.014
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发表时间：
2023
影响因子：
2
通讯作者：
Toro,DrewDel
中科院分区：
文献类型：
--
作者：
Leonard,JenniferM;Toro,DrewDel
认识到居住的微生物群落对人类健康和疾病做出了重大贡献，这是现代医学中正在出现的重大发现之一。这种细菌、古菌、真菌、病毒和真核生物的集合被称为微生物区系，它与它们所居住的单个组织一起被定义为我们的单个微生物组。现代DNA测序技术的最新进展使得识别、描述和表征这些微生物群落以及它们在个人和群体内和之间的变异成为可能。对人类微生物组的这种复杂理解得到了迅速扩大的调查领域的支持，并提供了显著影响各种疾病状态的治疗的潜力。这篇综述探讨了与人类微生物群的不同组成部分相关的最新发现，以及不同组织类型、个体和临床条件之间微生物群落的地理多样性。
The recognition that a resident community of microbes contributes substantially to human health and disease is one of the emerging great discoveries in modern medicine. This collection of bacteria, archaea, fungi, viruses, and eukaryotes are referred to as microbiota, which together with the individual tissues they inhabit is defined as our individual microbiome. Recent advances in modern DNA sequencing technologies permit the identification, description, and characterization of these microbial communities as well as their variations within and between individuals and groups. This complex understanding of the human microbiome is supported by a rapidly expanding field of inquiry and offers the potential to significantly impact the treatment of a wide variety of disease states. This review explores the recent findings associated with the various components of the human microbiome, and the geodiversity of microbial communities between different tissue types, individuals, and clinical conditions.