Roles for endocytosis in lentiviral replication.
Roles for endocytosis in lentiviral replication.
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DOI：
10.1016/s0962-8924(97)20038-3
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发表时间：
1997-01
影响因子：
19
通讯作者：
Hoxie JA
中科院分区：
文献类型：
--
作者：
Marsh M;Pelchen-Matthews A;Hoxie JA
内吞作用是许多病毒进入细胞所必需的。然而，灵长类慢病毒[人类免疫缺陷病毒(HIV)1和2，以及猴免疫缺陷病毒(SIV)]在其生命周期的其他方面使用内吞作用。在这里，作者描述了HIV和SIV利用内吞途径的方式，并讨论了内吞作用可能有助于这些病毒的致病特性的机制。
Endocytosis is essential for the entry of many viruses into cells. The primate lentiviruses [human immunodeficiency virus (HIV) 1 and 2, and the simian immunodeficiency viruses (SIVs)], however, use endocytosis in other aspects of their life cycles. Here, the authors describe the ways in which the endocytic pathway is used by HIV and SIV and discuss the mechanisms through which endocytosis may contribute to the pathogenic properties of these viruses.