A chest wall restrictor to study effects on pulmonary function and exercise - 1. Development and validation
A chest wall restrictor to study effects on pulmonary function and exercise - 1. Development and validation
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DOI：
10.1159/000029366
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发表时间：
1999-03-01
期刊：
影响因子：
3.7
通讯作者：
Arnall, DA
中科院分区：
文献类型：
--
作者：
Cline, CC;Coast, JR;Arnall, DA
胸壁限制性负荷降低了人在吸气时扩大胸壁的能力，导致肺容量、静息肺功能下降，最终影响运动表现。在某些形式的骨骼和肺部疾病（如脊柱侧凸）以及职业情况（如防弹背心）中观察到胸廓受限。我们设计了一种恒压胸壁限制装置，可在胸部上提供可量化和可重复的负荷。本文介绍了该装置和进行的初步肺功能测试。10名受试者参与了本研究。受试者在三种不同的情况下，在四种外部增加的限制性负荷下进行肺功能测试时佩戴限制性装置。双向重复测量多变量方差分析显示，每次负荷时用力呼气肺活量（FVC）和1 s用力呼气量（FEV1.0）显著降低，FEV1.0 / FVC比值（FEV1.0%）维持不变。没有发现任何变量在不同时间或坐姿和站立姿势之间有显著差异。这些结果表明，这种胸壁限制装置在呼吸循环中提供了可量化的吸入负荷增加，导致肺功能的可重复性下降，代表了一些限制性肺部疾病和职业情况。
Chest wall-restrictive loading reduces a person's ability to expand the chest wall during inhalation and results in decrements in lung capacities, resting pulmonary function, and ultimately, exercise performance. Chest walt restriction is observed in some forms of skeletal and pulmonary diseases (e.g., scoliosis) as well as in occupational situations (e.g., bulletproof vests). We have designed a constant-pressure chest wall-restrictive device that provides a quantifiable and reproducible load on the chest. This paper describes the device and the initial pulmonary function tests conducted. Ten subjects participated in this study. Subjects wore the restrictive device while performing pulmonary function tests at four externally added restrictive loads on three separate occasions. A two-way repeated-measures multivariate analysis of variance revealed significant decreases in forced expiratory vital capacity (FVC) and forced expiratory volume in 1 s (FEV1.0) at each load white the ratio of FEV1.0 to FVC (FEV1.0%) was maintained. No significant differences in any Variable were found across time or between the seated and standing position. These results indicate that this chest wall-restrictive device provides a quantifiable added inspiratory load in the breathing cycle that results in reproducible decrements in pulmonary function representative of those seen in some restrictive pulmonary disease and occupational situations.