Vitamins A and E serum levels in children and young adults with inflammatory bowel disease: Effect of disease activity
Vitamins A and E serum levels in children and young adults with inflammatory bowel disease: Effect of disease activity
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DOI：
10.1097/00005176-199802000-00002
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发表时间：
1998-02-01
影响因子：
2.9
通讯作者：
Leichtner, AM
中科院分区：
文献类型：
--
作者：
Bousvaros, A;Zurakowski, D;Leichtner, AM
背景：维生素缺乏症和脂溶性维生素缺乏症在成人炎症性肠病（IBD）中已有报道。进行了一项前瞻性研究，以确定患病率低的血清维生素A和E的儿童和年轻人与IBD。方法：临床信息和血清维生素水平前瞻性收集61例克罗恩病，36例溃疡性结肠炎，和23名对照组。确定IBD患者的疾病活动性和疾病部位。结果：维生素A缺乏症（定义为血清维生素A缺乏症）的患病率为100%（10/10），维生素A缺乏症的患病率为100%（10/10），维生素A缺乏症的患病率为100%（10/10
Background: Hypovitaminosis and fat-soluble vitamin deficiency have been reported in adults with inflammatory bowel disease (IBD). A prospective study was undertaken to determine the prevalence of low serum levels of vitamins A and E in children and young adults with IBD.Methods: Clinical information and serum for vitamin levels was gathered prospectively from 61 patients with Crohn's disease, 36 patients with ulcerative colitis, and 23 control subjects. Disease activity and disease location were determined for IBD patients. Serum retinol and alpha-tocopherol levels were determined by high-performance liquid chromatography.Results: The prevalence of hypovitaminosis A (defined as serum vitamin A