Ure(k)a! Sirtuins Regulate Mitochondria.
Ure(k)a! Sirtuins Regulate Mitochondria.
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DOI:
10.1016/j.cell.2009.04.036
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发表时间:
2009-05-01
期刊:
影响因子:
64.5
通讯作者:
Denu JM
中科院分区:
文献类型:
--
作者:
Hallows WC;Smith BC;Lee S;Denu JM
Increasing evidence suggests that multiple metabolic pathways are regulated by sirtuin-dependent protein deacetylation in the mitochondria. In this issue, show that an uncharacterized sirtuin, SIRT5, deacetylates and activates a mitochondrial enzyme, carbamoyl phosphate synthetase 1, which mediates the first step in the urea cycle.
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影响因子:
--
作者:
Smith, Brian C.;Hallows, William C.;Denu, John M.
通讯作者:
Denu, John M.
影响因子:
5.6
作者:
Schlicker, Christine;Gertz, Melanie;Steegborn, Clemens
通讯作者:
Steegborn, Clemens
影响因子:
4.8
作者:
Yu, Wei;Lin, Yan;Guan, Kun-Liang
通讯作者:
Guan, Kun-Liang
影响因子:
5.3
作者:
Lombard, David B.;Alt, Frederick W.;Schwer, Bjoern
通讯作者:
Schwer, Bjoern
DOI:
10.1073/pnas.0604392103
发表时间:
2006-07-05
影响因子:
11.1
作者:
Hallows, William C.;Lee, Susan;Denu, John M.
通讯作者:
Denu, John M.