Highly enantioselective epoxidation of multisubstituted enones catalyzed by non-heme iron catalysts.
Highly enantioselective epoxidation of multisubstituted enones catalyzed by non-heme iron catalysts.
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DOI：
10.1002/chem.201200992
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发表时间：
2012-06
期刊：
影响因子：
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通讯作者：
Bin Wang;Shoufeng Wang;C. Xia;Wei Sun
中科院分区：
文献类型：
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作者：
Bin Wang;Shoufeng Wang;C. Xia;Wei Sun
铁(II)效率：由脯氨酸和苯并咪唑衍生的N(4)配体的铁配合物对各种二取代和三取代烯酮的环氧化反应表现出前所未有的活性和对映体选择性(见图)。该系统以合成的非血红素铁催化剂为基础，提供了一系列高对映体纯度的环氧酮。
Iron(II) efficiency: The iron complexes of N(4) ligands, derived from proline and benzimidazole, exhibited an unprecedented activity and enantioselectivity for the epoxidation of a variety of di- and trisubstituted enones (see scheme). This system, based on synthetic non-heme iron catalysts, provides ready access to a wide range of epoxyketones of high enantiomeric purity.