Early diencephalon development in Alligator
Early diencephalon development in Alligator
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DOI：
10.1159/000108608
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发表时间：
2008-01-01
影响因子：
1.7
通讯作者：
Pritz, Michael B.
中科院分区：
文献类型：
--
作者：
Pritz, Michael B.
间脑的发展进行了研究，在爬行动物胚胎，短吻鳄mississipiensis，开始在一个单室阶段，并继续进行，直到内部的细分内存在的主要单位。采用多种形态学技术：免疫细胞化学、组织化学和甲酚紫染色。间脑开始是一个单一的单位。在横区，间脑随后分为两个：脑实质和联脑。然后，脑实质分裂成前脑实质和后脑实质。再晚些时候，中脑经历分块成前中脑和后中脑。随后，在这四个隔间中的每一个中发生内部细分。当间脑分成两个部分，并一直持续到每个单位都有内部分区时，可以看到一个纵向边界，将背侧（推测为背板）与腹侧（推测为基板）分开。没有明确的亚基可靠地确定在端脑或次级前脑在这段时期的早期发展的短吻鳄。鸟类（小鸡）和哺乳动物（人类）的早期间脑发育遵循类似的模式。具体来说，一个单一的间脑隔室分为两个区域：脑实质和联脑。随后，脑实质被细分为前部和后部单位。包括本研究在内的一些研究已经注意到，联脑进一步分为前部和后部，而其他研究则没有。尽管关于联脑是否是一个单一的单位存在差异，但这些对爬行动物（短吻鳄）、鸟类（鸡）和哺乳动物（人类）的详细分析表明，在哺乳动物中，间脑早期发育的初始模式是相似的。版权所有（c）2007 S. Karger AG，巴塞尔。
Diencephalon development was investigated in a reptilian embryo, Alligator mississipiensis, beginning at a single compartment stage and continuing until internal subdivisions were present within major units. A variety of morphological techniques were used: immunocytochemistry, histochemistry, and cresyl violet staining. The diencephalon begins as a single unit. In the transverse domain, the diencephalon subsequently divides into two: the parencephalon and the synencephalon. The parencephalon then splits into the parencephalon anterior and parencephalon posterior. Still later, the synencephalon undergoes parcellation into the synencephalon anterior and synencephalon posterior. Subsequently, internal subdivisions occur in each of these four compartments. When the diencephalon has become subdivided into two compartments and continuing until internal subdivisions are present in each unit, a longitudinal border separating a dorsal, presumed alar plate, from a ventral, presumed basal plate, was seen. No clear cut subunits were reliably identified in the telencephalon or secondary prosencephalon during this period of early development in Alligator. Early diencephalon development in birds (chick) and mammals (humans) follows a similar pattern. Specifically, a single diencephalic compartment divides into two zones: the parencephalon and synencephalon. Subsequently, the parencephalon becomes subdivided into an anterior and posterior unit. Some studies, including the present one, have noted further parcellation of the synencephalon into an anterior and posterior component, whereas others have not. Notwithstanding differences as to whether the synencephalon is a single unit or not, these detailed analyses in reptiles (Alligator), birds (chick), and mammals (humans), suggest that the initial pattern of early diencephalon development in amniotes is similar. Copyright (c) 2007 S. Karger AG, Basel.