07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived xylariaceous fungus LL-07H239

07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived xylariaceous fungus LL-07H239
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DOI:
10.1021/np049924g
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发表时间:
2004-09-01
影响因子:
5.1
通讯作者:
Carter, GT
Carter, GT
中科院分区:
生物学2区
文献类型:
--
作者:
McDonald, LA;Barbieri, LR;Carter, GT

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07 H239-A(1)是一种来自海洋来源的木霉菌的新的eremophilane倍半萜,经分离、表征并显示对多种癌细胞系具有细胞毒性,对CCRFCEM白血病细胞系具有一定的选择性(IC 50 = 0.9 μ g/mL)。
07H239-A (1), a new eremophilane sesquiterpene from a marine-derived xylariaceous fungus, was isolated, characterized, and shown to be cytotoxic toward a variety of cancer cell lines, with some selectivity for a CCRFCEM leukemia line (IC50 = 0.9 mug/mL).