Highly Efficient F, Cu doped TiO2 anti-bacterial visible light active photocatalytic coatings to combat hospital-acquired infections.
Highly Efficient F, Cu doped TiO2 anti-bacterial visible light active photocatalytic coatings to combat hospital-acquired infections.
复制标题
高效 F、Cu 掺杂 TiO2 抗菌可见光活性光催化涂层，可对抗医院获得性感染。
DOI：
10.1038/srep24770
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发表时间：
2016-04-21
影响因子：
4.6
通讯作者：
Pillai SC
中科院分区：
文献类型：
--
作者：
Leyland NS;Podporska-Carroll J;Browne J;Hinder SJ;Quilty B;Pillai SC
细菌感染是包括医院在内的医疗机构中患者健康的主要威胁。患者发病的主要原因之一是感染金黄色葡萄球菌。据报道，最主要的医院细菌之一，耐甲氧西林金黄色葡萄球菌（MRSA）在医院表面（例如隐私窗玻璃）上存活长达5个月。目前的抗菌技术都不能有效地消除金黄色葡萄球菌。在浮法玻璃上制备了一种新型的氟铜共掺杂二氧化钛透明、固定化、超亲水涂层。抗菌活性已被证明（通过使用金黄色葡萄球菌），这是由可见光激活（VLA）和铜离子毒性的组合引起的。与纯氟掺杂的VLA光催化剂相比，铜和氟的共掺杂已显示出改善涂层的性能。在可见光照射下和log10 = 1.8在黑暗中的细菌种群的减少已经实现，与log10 = 1.8在可见光照射下，没有活动，对于纯氟掺杂的二氧化钛相比。光催化涂层中活性氧的产生是显著减少玻璃表面细菌生长的主要因素。
Bacterial infections are a major threat to the health of patients in healthcare facilities including hospitals. One of the major causes of patient morbidity is infection with Staphylococcus aureus. One of the the most dominant nosocomial bacteria, Methicillin Resistant Staphylococcus aureus (MRSA) have been reported to survive on hospital surfaces (e.g. privacy window glasses) for up to 5 months. None of the current anti-bacterial technology is efficient in eliminating Staphylococcus aureus. A novel transparent, immobilised and superhydrophilic coating of titanium dioxide, co-doped with fluorine and copper has been prepared on float glass substrates. Antibacterial activity has demonstrated (by using Staphylococcus aureus), resulting from a combination of visible light activated (VLA) photocatalysis and copper ion toxicity. Co-doping with copper and fluorine has been shown to improve the performance of the coating, relative to a purely fluorine-doped VLA photocatalyst. Reductions in bacterial population of log10 = 4.2 under visible light irradiation and log10 = 1.8 in darkness have been achieved, compared with log10 = 1.8 under visible light irradiation and no activity, for a purely fluorine-doped titania. Generation of reactive oxygen species from the photocatalytic coatings is the major factor that significantly reduces the bacterial growth on the glass surfaces.