Luteolin and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells
Luteolin and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells
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DOI：
10.1023/b:mcbi.0000044364.73144.fe
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发表时间：
2004-10-01
影响因子：
4.3
通讯作者：
Kitts, DD
中科院分区：
文献类型：
--
作者：
Hu, C;Kitts, DD
活性氧和氮衍生的活性物质在生理和病理生理条件中起着重要作用。黄酮类化合物，木犀草素和木犀草素-7-O-葡萄糖苷沿着与两种黄酮的丰富的植物来源，即蒲公英（蒲公英）花提取物，在不同的体外模型系统的抗氧化活性进行了研究。在本研究中，毛地黄黄酮和毛地黄黄酮-7-O-葡萄糖苷在浓度低于20 μ M时，显著（p
Both reactive oxygen- and nitrogen-derived reactive species play important roles in physiological and pathophysiological conditions. Flavones, luteolin and luteolin-7-O-glucoside along with a rich plant source of both flavones, namely dandelion (Taraxacum officinale) flower extract were studied for antioxidant activity in different in vitro model systems. In this current study, luteolin and luteolin-7-O-glucoside at concentrations lower than 20 muM, significantly (p