Extended focus high-speed swept source OCT with self-reconstructive illumination
Extended focus high-speed swept source OCT with self-reconstructive illumination
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DOI：
10.1364/oe.19.012141
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发表时间：
2011-06-20
期刊：
影响因子：
3.8
通讯作者：
Leitgeb, Rainer A.
中科院分区：
文献类型：
--
作者：
Blatter, Cedric;Grajciar, Branislav;Leitgeb, Rainer A.
我们提出了一个贝塞尔光束照明FDOCT设置使用FDML扫频源在1300 nm，高达440 kHz的A-扫描速率，并讨论其优势的高散射样品的结构和功能成像。由于贝塞尔光束在大的深度范围内保持其横向延伸，因此实现了扩展的焦点。此外，贝塞尔光束表现出自重构特性，即使在皮肤上的毛发等障碍物后面也可以成像。将照明与高斯检测解耦增加了全局灵敏度并实现暗场成像。暗场成像有助于避免来自样品表面的强烈反射，由于高速8位采集卡的有限动态范围，这些反射会对灵敏度产生不利影响。此外，使用B扫描间散斑方差分析，显示了具有高灵敏度的对比毛细管的可能性。我们展示了扩展焦点配置的固有优势，特别是减少血管下方的相位去相关效应，从而提高轴向血管的清晰度。(C)2011年美国光学学会
We present a Bessel beam illumination FDOCT setup using a FDML Swept Source at 1300nm with up to 440kHz A-scan rate, and discuss its advantages for structural and functional imaging of highly scattering samples. An extended focus is achieved due to the Bessel beam that preserves its lateral extend over a large depth range. Furthermore, Bessel beams exhibit a self-reconstruction property that allows imaging even behind obstacles such as hairs on skin. Decoupling the illumination from the Gaussian detection increases the global sensitivity and enables dark field imaging. Dark field imaging is useful to avoid strong reflexes from the sample surface that adversely affect the sensitivity due to the limited dynamic range of high speed 8bit acquisition cards. In addition the possibility of contrasting capillaries with high sensitivity is shown, using inter-B-scan speckle variance analysis. We demonstrate intrinsic advantages of the extended focus configuration, in particular the reduction of the phase decorrelation effect below vessels leading to improved axial vessel definition. (C) 2011 Optical Society of America