Do prognoses of patients with second primary cancers differ from those of patients with no prior cancer? A population-based study
Do prognoses of patients with second primary cancers differ from those of patients with no prior cancer? A population-based study
复制标题
DOI：
10.1016/j.canep.2022.102218
复制
发表时间：
2022-07-20
影响因子：
2.6
通讯作者：
Miyashiro, Isao
中科院分区：
文献类型：
--
作者：
Kudo, Haruka;Morishima, Toshitaka;Miyashiro, Isao
背景：一些癌症幸存者发展为第二原发癌。然而，尚未确定既往患有癌症和未患有癌症的患者之间的预后差异。我们检查并比较了这些patients.Methods的发病情况：使用大坂府癌症登记处和日本生命统计局的记录链接数据库，我们确定了1995-2009年期间被诊断为胃癌（n = 70，946），结直肠癌（n = 60，582）或肺癌（n = 58，016）的年龄≥ 40岁的患者。我们将这些癌症定义为索引癌症。根据既往癌症史和指数诊断与既往癌症之间的间隔，将患者分为三组：单一（无既往癌症或间隔>= 10年）、同步（间隔>= 10年）、
Background: Some cancer survivors develop second primary cancers. However, differences in prognosis between patients who have and have not had prior cancer have not been established. We examined and compared the prognoses of such patients.Methods: Using the record-linked database of the population-based Cancer Registry of Osaka Prefecture and Vital Statistics in Japan, we identified patients aged >= 40 years who were diagnosed with stomach (n = 70,946), colorectal (n = 60,582), or lung (n = 58,016) cancers during 1995-2009. We defined these cancers as index cancers. Patients were classified into three groups according to history of prior cancer and interval between diagnosis of index and prior cancer: single (no prior cancer or interval of >= 10 years), synchronous (interval