Detection of human papillomavirus DNA on the fingers of patients with genital warts
Detection of human papillomavirus DNA on the fingers of patients with genital warts
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DOI：
10.1136/sti.75.5.317
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发表时间：
1999-10-01
影响因子：
3.6
通讯作者：
Gray, JJ
中科院分区：
文献类型：
--
作者：
Sonnex, C;Strauss, S;Gray, JJ
目的：了解生殖器尖锐湿疣患者手指上是否携带人乳头状瘤病毒(HPV)DNA。方法：对14例男性和8例女性生殖器尖锐湿疣患者的生殖器皮损、指尖和指甲尖进行细胞刷检。结果：所有女性生殖器标本中均检出HPVDNA，14例男性生殖器标本中检出13例。在三名女性和九名男性的指刷样本中检测到HPV DNA。在1名女性和5名男性的生殖器和手部样本中发现了相同的HPV类型。结论：本研究确定了生殖器尖锐湿疣患者手携带的生殖器HPV类型。虽然性交被认为是传播生殖器HPV感染的常见方式，但我们的发现提高了通过手指与生殖器接触传播的可能性。
Objective: To determine whether patients with genital warts carry human papillomavirus (HPV) DNA on their fingers.Methods: 14 men and eight women with genital warts had cytobrush samples taken from genital lesions, finger tips, and tips of finger nails. Samples were examined for the presence of HPV DNA by the polymerase chain reaction.Results: HPV DNA was detected in all female genital samples and in 13/14 male genital samples. HPV DNA was detected in the finger brush samples of three women and nine men. The same HPV type was identified in genital and hand samples in one woman and five men.Conclusion: This study has identified hand carriage of genital HPV types in patients with genital warts. Although sexual intercourse is considered the usual mode of transmitting genital HPV infection, our findings raise the possibility of transmission by finger-genital contact.