AMPUTATION LEVEL OF DENTAL PULP FOR HARD TISSUE FORMATION WITH TETRACALCIUM PHOSPHATE / TWO-FOLD CONCENTRATION OF MCILVAIN’S BUFFERED SOLUTION
AMPUTATION LEVEL OF DENTAL PULP FOR HARD TISSUE FORMATION WITH TETRACALCIUM PHOSPHATE / TWO-FOLD CONCENTRATION OF MCILVAIN’S BUFFERED SOLUTION
复制标题
使用磷酸四钙/两倍浓度的 MCILVAIN 缓冲溶液形成硬组织的牙髓截肢水平
DOI：
10.1142/9789814291064_0075
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
T. Toda
中科院分区：
文献类型：
--
作者：
M. Yoshikawa;Y. Mandai;Y. Hiraoka;Harunobu Oonishi;T. Toda
在大鼠下颌第一磨牙根管内进行不同水平的牙髓切断，以确定切断水平与硬组织形成之间是否存在相关性。将含有磷酸四钙的粘固剂（TeDC-Mc）放置在切断的牙髓的表面上，并用光固化树脂密封腔室。术后3周，TeDC-Mc组根管口硬组织形成率为100%，根管中部硬组织形成率为85%。在根尖孔处离断牙髓的病例中，15.8%的病例发现有硬组织增加。根髓显示坏死，在封闭腔室的情况下，在已在管口处切断的根管内未观察到硬组织的增加。在根尖孔以外的根尖周区域植入TeDC-Mc，95%的牙槽骨重建在后期被识别。牙髓中未分化的间充质细胞和成牙本质细胞的活性可能参与硬组织的形成。由于缺乏未分化的间充质细胞，牙槽骨重建需要较长的时间。
The pulp was amputated at several levels in mandibular first molar canals of rats to determine whether a correlation exists between the amputation level and hard tissue formation. Tetracalcium phosphate containing cement (TeDC-Mc) was placed on a surface of amputated pulp and the chambers were sealed with a light curing resin. Histopathological procedures were performed after 1, 2, 3 and 4 weeks of pulp treatments.Three weeks after the operation, hard tissue formed in 100% in the case placed TeDC-Mc at the root canal orifice, and formed in 85% of the case at the middle portion. In the case of pulp amputated at the apical foramen, addition of hard tissue was recognized in 15.8%. Radicular pulp exhibited necrosis and no addition of hard tissue was observed in the canals that had been amputated at the canal orifice with sealing of the chamber. In the periapical area instrumented beyond the apical foramen and placed TeDC-Mc, reconstruction of the alveolar bone was recognized at a later period in 95 %. The activity of undifferentiated mesenchymal cells and odontoblasts in dental pulp might contribute to hard tissue formation. Long periods are required for reconstruction of alveolar bone because of a lack of undifferentiated mesenchymal cells.