Drainage-related Complications in Percutaneous Transhepatic Biliary Drainage An Analysis Over 10 Years
Drainage-related Complications in Percutaneous Transhepatic Biliary Drainage An Analysis Over 10 Years
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DOI：
10.1097/mcg.0000000000000275
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发表时间：
2015-10-01
影响因子：
2.9
通讯作者：
Neu, Bruno
中科院分区：
文献类型：
--
作者：
Nennstiel, Simon;Weber, Andreas;Neu, Bruno
背景：经皮经肝胆管胆道引流术（PTBD）的手术相关并发症在文献中已有详细记录。然而，关于长期PTBD治疗中引流相关并发症发生率的数据相对有限。本回顾性研究评估的程度和性质的引流并发症PTBD治疗和相关的危险因素，这些complications.Patients和方法：1997年6月至2007年5月，共385例PTBD患者通过分析PTBD数据库和医院图表，共2468经皮胆道引流被identified.Results：在确定的患者，243（63%）有恶性和142（37%）良性胆管狭窄。在40%的患者中观察到至少1例引流相关并发症。就引流管总数而言，假体并发症发生率为23%。闭塞、脱位和胆管炎是PTBD治疗期间观察到的最常见并发症。胆管炎和闭塞的危险因素是恶性疾病、既往并发症和双侧引流。胆道系统近端狭窄接近显着。结论：引流相关并发症是PTBD治疗的主要问题。本研究中发现的阻塞和胆管炎的危险因素有助于改进个体策略以降低这些引流并发症的发生率。
Background:Procedure-related complications of percutaneous transhepatic biliary drainage (PTBD) have been well documented in the literature. However, relatively restricted data are available concerning drainage-related complication rates in long-term PTBD therapy. The present retrospective study evaluated the extent and the nature of drainage complications during PTBD therapy and associated risk factors for these complications.Patients and Methods:Between June 1997 and May 2007, a total of 385 patients with PTBD were identified by analyzing the PTBD database and hospital charts, with a total of 2468 percutaneous biliary drainages being identified.Results:Among the identified patients, 243 (63%) had malignant and 142 (37%) had benign bile duct strictures. At least 1 drainage-related complication was observed in 40% of the patients. With respect to the total number of drains, prosthesis complications occurred in 23%. Occlusion, dislocation, and cholangitis were the most common complications observed during PTBD therapy. Risk factors for cholangitis and occlusion were malignant disease, prior occurrence of complications, and bilateral drainage. Proximal stenosis of the biliary system was close to significant.Conclusions:Drainage-related complications are a major problem in PTBD therapy. The risk factors for occlusion and cholangitis discovered in this study can help to refine individual strategies to reduce the rate of these drainage complications.